摘要
目的对郴州市2006-2009年流行性感冒流行病学和病原学监测结果进行分析。方法采集流感样病例(ILI)的鼻、咽拭子标本用狗肾细胞(MDCK)进行病毒分离培养,采用血凝(HA)及血凝抑制(HI)方法进行病毒初筛及分型鉴定。结果 2006-2009年4所哨点医院共报告ILI 21 960例,平均ILI就诊百分比为2.30%,共检测ILI鼻、咽拭子标本5 350份,分离到季节性流感阳性毒株607株,阳性率11.35%,主要流行毒株为A(H1N1)和A(H3N2),在不同年份交替流行,其次每年都有B型流感病毒存在。疑似流感疫情标本1 228份,阳性毒株779份,阳性率63.44%,2006-2008年郴州市流感暴发疫情以B型为主,2009年郴州市流感暴发疫情以甲型H1N1型为主,季节性流感病毒也较活跃。结论 2006-2009年郴州市流行的流感毒株主要有季节性H1N1亚型、H3N2亚型、B型流感病毒和甲型H1N1流感病毒4种,流感流行有明显的季节性,暴发疫情主要发生在学校。
Objective To analyze the epidemiology and etiological monitoring results of influenza virus in Chenzhou during the period of 2006～2009. Methods Nasal swabs or throat swabs were collected from patients with influenza-like illness（ILI）,and then inoculated in Madin-Darby canine kidney（MDCK） cell lines.The types of influenza were identified by hemagglutination（HA） and hemagglutination inhibition（HA） tests. Results Totally 21,960 cases of ILI were reported from the 4 sentinel hospitals during the period of 2006～2009,and the average percentage of ILI visitors was 2.30%.A total of 5,350 nasal swabs or throat swabs were detected,of which 607 strains（11.35%） were seasonal influenza viruses.The seasonal A-H1N1 and A-H3N2 viruses were alternately performed as the main epidemic strains which accompanied with the influenza B viruses in Chenzhou.1,228 samples from the outbreaks of influenza were collected,of which 779 samples（63.44%） were positive.Influenza B virus was the main strain in outbreaks during the period of 2006～2008,while it was changed to novel influenza A/H1N1 virus in 2009. Conclusions During the period of 2006～2009,the epidemical influenza virus in Chenzhou were the seasonal A-H1N1,A-H3N2,B viruses and the novel influenza A/H1N1 virus.The outbreak of influenza mainly took place in schools.
出处
《实用预防医学》
CAS
2011年第5期806-809,共4页
Practical Preventive Medicine
