摘要
创伤后应激障碍(PTSD)是军人应对突发事件后常见、反复发作的慢性精神障碍,有较高的自杀率与功能损害。由于人们对PTSD有很多误解,所以治疗存在较多困难。近年来,PTSD在神经生物学方面有了更多新发现,芍药苷单体成分具有显著的抗抑郁、抗焦虑和神经保护作用,临床症状完全缓解或大部分消除及功能康复是可期待的。芍药在抗PTSD方面有着广阔的应用前景,有希望将芍药及其有效成分开发成临床效果显著、低毒高效、药效持久的抗PTSD制剂。
Post-traumatic stress disorder（PTSD） is a common,recurrent chronic mental disorder which occurs in military who suffers from sudden events,leading to a high frequency of suicide and funtional impairment.As there is much misunderstanding on PTSD,more difficulties are encountered in the treatment.Lately,there are many new discoveries in neurobiology,including peoniflorin monomer′s distinguished effect on anti-depression,anti-anxiety and neural protection.It is very likely that the symptoms will be completely relieved or mostly eliminated and the functional rehabilitation is in the horizon.Paeonia lactiflora pall has a wide application prospect in anti-PTSD field,and the exploration of the effective components and the development of a highly effective preparation with low side-effects and great clinical significance is expected.
出处
《医学综述》
2011年第10期1514-1516,共3页
Medical Recapitulate
关键词
创伤后应激障碍
治疗
军事医学
芍药苷
Post-traumatic stress disorder
Therapy
Military medicine
Peoniflorin
