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伊立替康联合紫杉醇治疗复发上皮性卵巢癌的疗效观察 被引量:6

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摘要 目的观察伊立替康联合紫杉醇治疗复发上皮性卵巢癌的疗效。方法选择30例复发的耐铂上皮性卵巢癌,采用伊立替康联合紫杉醇治疗。伊立替康80mg/m2,静脉给药,第1、8、15天,28d为1周期;紫杉醇用药剂量和方法:每疗程紫杉醇总剂量为135mg/m2,溶于500ml 0.9%氯化钠溶液或5%葡萄糖液中进行静脉滴注,2~4个周期结束后评价疗效。结果 30例均可评价疗效,完全缓解率为6.67%,部分缓解率为23.33%,总缓解率43.33%,中位肿瘤进展时间为6.8个月。不良反应主要为骨髓抑制和迟发性腹泻,无化疗毒性相关死亡病例。结论伊立替康单药是治疗复发的耐铂上皮性卵巢癌安全有效的方案。
作者 于波
出处 《实用心脑肺血管病杂志》 2011年第6期943-944,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
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