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降钙素原在肾移植术后患者肺部感染诊断中的应用 被引量:28

Application of procalcitonin to the diagnosis of pneumonia in patients after kidney transplantation
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摘要 目的研究血清降钙素原(PCT)在肾移植术后并发肺部感染患者诊断中的实用价值。方法回顾性研究肾移植术后并发肺部感染患者102例,根据肺部感染的病原体诊断标准分为细菌组(32例)和非细菌组(70例),检测并比较两组PCT和C-反应蛋白(CRP)值,将两组数据进行统计学比较。结果肾移植术后并发肺部细菌感染患者血清中PCT增高较非细菌组差异具有统计学意义(P〈0.01)。CRP增高较非细菌组差异无统计学意义(P〉0.05)。比较32例肾移植术后并发肺部细菌感染患者血清中PCT增高例数和CRP增高例数差异无统计学意义,不存在一致性。结论PCT对肾移植术后是否并发肺部细菌感染患者具有明显的临床诊断价值。 Objective To evaluate the practical value of procalcitonin (PCT) in diagnosis of pneumonia in patients after kidney transplantation. Method A total of 102 patients with pneumonia after kidney transplantation were reviewed. According to the diagnostic criteria of pathogens of pneumonia, 32 patients were enrolled in bacterial group and 70 patients in non-bacterial group. The data of the PCT level and the C-reactive protein (CRP) level of the two groups were determined and compared with each other. Results There was significant difference in PCT level between bacterial pneumonia patients after kidney transplantation and non-bacterial pneumonia patients group ( P 〈 0. 01 ). The difference in CRP level between bacterial pneumonia patients after kidney transplantation and non-bacterial pneumonia patients group was not significant ( P 〉 0.05 ). The changes of PCT level and the CRP level in 32 patients with bacterial pneumonia after kidney transplantation were not significant ( P 〉 0.05 ), and they were not associated with each other. Conclusions Monitoring the PCT level in patients with bacterial pneumonia after kidney transplantation would have an obviously clinical significance in diagnostic value.
出处 《中华急诊医学杂志》 CAS CSCD 北大核心 2011年第5期524-527,共4页 Chinese Journal of Emergency Medicine
关键词 降钙素原 肾移植 肺部细菌感染 C-反应蛋白 Procalcitonin Kidney transplantation Bacterial pneumonia C-reactive protein
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