摘要
目的观察汉防已甲素气雾剂治疗支气管哮喘和喘息型慢性支气管炎的临床疗效。方法438例患者治疗前详细记录病史,在治疗前和治疗后1、3、5、10、20min各记录喘息、程度及哮鸣音分布情况,治疗前和治疗后10、20min各记录呼吸次数和心率。结果即时平喘疗效与愈喘气雾组比较,总有效率和显效以上率无明显差异（P〉0.05）,与空白对照气雾剂组比较,则有极显著性差异（P〈0.001）;肺功能疗效的VC、FEV1、MMEF、FEV75~85%各均值治后较治前均略有升高,但统计学处理无明显差异（P〉0.05）;起效和维持时间1~2h以上,少数病例可维持24h。结论汉防已甲素气雾剂的平喘效果是确切的并有肺通气功能的作用,而肺功能变化不明显。
Objective To observe the clinical efficacy of tetrandrine prime aerosol in treatment of bronchial asthma and wheezing of chronic bronchitis.Methods Totally 438 cases medical history recorded before treatment,before and after treatment of 1,3,5,10,20-minute noted all records,extent and distribution of asthmatic wheeze,treatment,10,20 minutes before and after treatment,the records of respiratory frequency and heart rate.Results Immediate effect and the more breath fog asthma group,the total effective rate and markedly effective rate was no significant difference above（P0.05）,compared with the control aerosol,there was significant difference（P0.001）;lung functional effects of VC,FEV1,MMEF,FEV75~85% higher than the average,post-treatment were slightly higher before treatment,but no statistically significant difference（P0.05）;onset and duration 1~2 hours,a few cases can be maintained for 24 hours.Conclusions Tetrandrine asthma aerosol effect is precise and has the role of pulmonary function,and lung function did not change significantly.
出处
《医药论坛杂志》
2011年第5期74-76,共3页
Journal of Medical Forum
