摘要
目的 分析眼眶原发恶性淋巴瘤的治疗方法。方法 15 例眼眶原发恶性淋巴瘤均为非霍奇金淋巴瘤。 Ann Arbor 分期:Ⅰ A 期11 例,Ⅱ A 期4 例。放射治疗剂量30 ~58 Gy ,3 ~6 周。结果 1 ,3 ,5 年局部控制率分别为94 .1 % ,92 .3 % 和92 .3 % 。3 ,5 ,10 年生存率分别为100 % ,90 % 和75 % 。有5 例疾病进展。结论 放射治疗为主要治疗手段。推荐放射治疗剂量为35 ~45 Gy ,3 .5 ~4 .5 周。不需行淋巴引流区预防照射。对恶性程度高及有眶外侵犯者应加化疗。
Objective To analyze the treatment of primary orbital lymphoma.Methods Fifteen patients with primary orbital lymphoma were treated from 1981~1997.All had non Hodgkin's lymphoma (NHL) and received radiotherapy . A total dose of 30~58?Gy(median 50?Gy),3~6 weeks was delivered. Results The 1 ,3 and 5 year local control rates were 94.1%,92.3% and 92.3%.The overall 3 ,5 ,10 year survival rates were 100%,90%and 75%,respectively. Conclusions Excellent local control and long term survival can be achieved by radiation.35~45?Gy appears to be a sufficient dose.The late complications were cataract and lacrimal dysfunction. Chemotherapy should be given to those patients with poor differentiation or systematic spread.
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
1999年第3期147-148,共2页
Chinese Journal of Radiation Oncology
关键词
淋巴瘤
放射疗法
眼眶肿瘤
恶性肿瘤
Lymphoma/radiotherapy
Orbital neoplasms/radiotherapy