摘要
目的 分析１２ 例眼眶原发恶性淋巴瘤的放射治疗结果，复习文献，讨论眼眶恶性淋巴瘤的治疗方法。方法 １９５８ 年至１９９７ 年中国医学科学院肿瘤医院收治眼眶原发恶性淋巴瘤１２ 例，Ⅰ期８ 例，Ⅱ期４ 例。１０ 例行单纯放射治疗，２ 例行放射治疗加化疗。放射治疗主要为局部照射，照射剂量 Ｄ Ｔ３０ ～６０ Ｇｙ 。结果 局部控制率１００ ％ ，５ 年生存率８６ ％ 。文献复习显示，眼眶原发恶性淋巴瘤７５ ％ 为低度恶性，单纯放射治疗局部控制率平均９７ ％ ，５ 年生存率６２ ％ ～９３ ％ ，远处复发率为２０ ％ 。结论 局部放射治疗是眼眶原发恶性淋巴瘤有效的治疗方法，低度恶性放射剂量 Ｄ Ｔ ３０ ～３５ Ｇｙ ，中、高度恶性 Ｄ Ｔ ３６ ～４０ Ｇｙ 。
Objective To evaluate the treatment results of our twelve primary orbital lymphoma.Methods From 1958 1997, 12 patients with primary orbital lymphoma were treated. Eight cases had Stage I lesions and four had Stage Ⅱ lesions. Ten patients received radiotherapy alone (30～60 Gy,4～8 weeks) and 2 patients received radiotherapy plus chemotherapy.Results Local control rate was 100% and 5 year survival was 86%. Literature is reviewed. About 75% of orbital lymphoma is pathologically low grade. Local irradiation could nearly give 100% local control with 62%～93% 5 year survival rate. Distant relapse is about 20%.Conclusions Carefully planned radiotherapy with lens shielding is an effective and safe treatment in the management of orbital lymphoma. Radiation doses of 30～35?Gy for low grade lesions and 36～40?Gy for intermediate and high grade lesions are recommended.
出处
《中华放射肿瘤学杂志》
CSCD
北大核心
1999年第3期149-151,共3页
Chinese Journal of Radiation Oncology
关键词
淋巴瘤
放射疗法
眼眶肿瘤
恶性肿瘤
Lymphoma/radiotherapy
Orbital neoplasms/radiotherapy
