摘要
目的分析缺血性进展性脑卒中的相关危险因素,为探讨缺血性进展性脑卒中的发病机制提供参考。方法对356例缺血性进展性脑卒中患者的临床资料进行回顾性分析,入选患者分为进展性脑卒中组(进展组)和非进展组,按OCSP分为四型,比较各亚型的发生率,对缺血性进展性脑卒中的相关因素进行Logistic回归分析,筛选缺血性进展性脑卒中发生的危险因素。结果完全前循环梗死亚型进展性脑卒中发病率最高,与其它亚型比较差异有显著性(P<0.05);部分前循环梗死亚型进展性脑卒中发病率高于腔隙性梗死和后循环梗死亚型(P<0.05),但后两者之间差异无显著性。进展组高血压史和颈动脉粥样硬化发生率显著高于非进展组(P<0.05),进展组入院时血糖、胆固醇、甘油三酯、纤维蛋白原水平显著高于非进展组(P<0.05);颈动脉粥样硬化和高血糖是缺血性进展性脑卒中发生的危险因素。结论 OCSP各亚型进展性脑卒中发病率各不相同,完全前循环梗死亚型进展性脑卒中发病率最高;颈动脉粥样硬化和高血糖是缺血性进展性脑卒中发生的危险因素。
Aim To study the risk factors of progressive ischemic stroke（PIS） and provide reference for the mechanism of PIS. Methods 356 cases of PIS patients were analyzed retrospectively and were divided into progress groups and non-progress group with four types according to OCSP.Compared the incidence of various subtype,the related factors of PIS were analyzed by logistic regression method,screening PIS risk factors. Results The incidence of TACI subtype was the highest than that of the other subtypes（P〈0.05）. The hypertension history and the incidence of carotid atherosclerosis in the progress groups were significantly higher than that of the non-progress group（P〈0.05）,the blood glucose,cholesterol,triglycerides and fibrinogen level in the progress groups were significantly higher than that of the non-progress group（P〈0.05）.Carotid atherosclerosis and high blood sugar were the risk factors of PIS. Conclusion The incidence of PIS in the OCSP subtypes was varied;the incidence of PIS was the highest in the TACI subtype;Carotid atherosclerosis and high blood sugar were the risk factors of PIS.
出处
《中国动脉硬化杂志》
CAS
CSCD
北大核心
2011年第4期336-338,共3页
Chinese Journal of Arteriosclerosis
