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p57蛋白检测对水泡状胎块诊断和分型的意义 被引量:4

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摘要 水泡状胎块(hydatidiform mole)也称葡萄胎,是指绒毛水肿及不同程度的滋养叶细胞增生的异常胎盘,是最常见的妊娠滋养细胞疾病,我国水泡状胎块的发病率为1∶1290次妊娠.按遗传物质来源可将水泡状胎块分为遗传物质来自父方和来自双亲两类,即:完全性水泡状胎块(C水泡状胎块)和部分性水泡状胎块(P水泡状胎块).两者在形态学上鉴别存在困难,但两者恶变率不同,预后存在明显差异.p57基因是细胞周期蛋白依赖性激酶抑制因子(CDKI)家族成员,参与细胞周期调控,
出处 《中华妇产科杂志》 CAS CSCD 北大核心 2011年第4期279-280,共2页 Chinese Journal of Obstetrics and Gynecology
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