摘要
目的 了解实施全民食盐加碘后学龄儿童智商变化情况,为碘缺乏病防治工作提供科学依据.方法 2006-2009年选择辽宁省大连市11所小学校1580名儿童,采用中国联合型瑞文测验第二次修订版（CRT-C2）测验智商.智商分度及标准：非常优秀（≥130）、优秀（120～129）、中上（110～119）、中等（90～109）、中下（80～89）、边缘（70～79）、智力落后（≤69）.采集儿童随意1次尿样（2006年未开展尿碘监测）,用砷铈催化分光光度法检测尿碘.按监测年份及儿童出生年份分析全民食盐加碘前后儿童智商增长特点.结果 2006-2009年8～10岁儿童智商值分别为110.4 4-14.0、112.5±12.4、117.2 ±11.4、116.2±12.6,呈逐年增长趋势：2007-2009年与2006年比较年均增长值分别为2.1、3.4、1.9个智商点.2007-2009年8～10岁儿童尿碘中位数分别为224.7、266.7、222.1μg/L,均在200～300μg/L,人群碘营养处于超足量水平.1994-2000年出生的儿童智商值分别为106.7±13.0、108.1 ±13.9、108.5±134、111.3±14.3、113.6±12.5、115.3±12.3、119.8±11.2;1995-2000年与1994年比较年均增长值分别为1.4、0.9、1.5、1.7、1.7、2.2个智商点;智力落后和边缘智力的比例各年度均〈2%;优秀和非常优秀的检出率呈逐年上升趋势,中等和中下的检出率呈逐年下降趋势（x2值分别为52.471、34.329、66.483、11.148,P均〈0.01）.结论 全民食盐加碘可快速提高学龄儿童智商水平.在碘缺乏病防治工作中,应加强智商指标的监测和应用.
Objective To obtain scientific data for control of iodine deficiency disorders（IDD） by reviewing the surveillance information of school children intelligence quotient（IQ） after the implementation of universal salt iodization. Methods One thousand five hundred and eighty children were selected from 11 primary school in Dalian city of Liaoning province during 2006 to 2009. IQ was measured by Combined Raven Test-C2（CRT-C2） in China. Groups of IQ were classified as outstanding（≥ 130）, excellent （120- 129）, above average （110- 119）, average （90 - 109）, below average（80 - 89）, margin（70 - 79）, low（≤69）. Urinary samples of children were collected randomly. Urinary iodine were determined by As-Ce catalytic spectrophotometry. The growth characteristics of IQ were analyzed according to surveillance year and born year. Results The average IQ of children aged 8-10 were 110.4 ± 14.0,112.5 ± 12.4,117.2 ± 11.4,116.2 ± 12.6, respectively, increased year by year from 2006 to 2009. Its average annual increase from 2007 to 2009 were 2.1,3.4,1,9 compared with the IQ in 2006 respectively. The medians of urinary iodine were 224.7,266.7,222.1 μg/L from the year 2007 to 2009, respectively, which were all between 200 - 300 μg/L and can be classified as more than adequate level. The average IQ of children born during the year of 1994 to 2000 were 106.7 ± 13.0,108.1 ± 13.9,108.5 ± 13.4,111.3 ± 14.3,113.6 ± 12.5,115.3 ± 12.3,119.8 ± 11.2, respectively. Its average annual increase from 1995 - 2000 were 1.4,0.9,1.5,1.7,1.7,2.2 compared with the IQ born in 1994 respectively. The ratio of IQ in margin group and low group were all below 2% ; the ratio was increasing in excellent group and outstanding group and decreasing in average group and below average group significantly year after year（x2 = 52.471,34.329,66.483,11.148, all P〈0.01）. Conclusions Universal salt iodization improves IQ scores. IQ index should be brought into the surveillance project and put in use in IDD control.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2011年第3期319-322,共4页
Chinese Jouranl of Endemiology
关键词
碘
缺乏症
盐类
智力
Iodine
Deficiency diseases
Salts
Intelligence
