摘要
目的:探讨利用七氟醚复合小剂量舒芬太尼对小儿腹股沟区手术全麻的临床效果。方法:将96例患儿随机分为三组,各32例,分别为七氟醚复合小剂量舒芬太尼复合组、七氟醚组和氯胺酮组。氯胺酮组患儿采用5 mg/kg氯胺酮肌注麻醉,七氟醚组通过面罩吸入七氟醚实施麻醉,复合组在七氟醚组的麻醉方法基础上,于切皮前辅助采用0.2μg/kg舒芬太尼进行缓慢静注。结果:氯胺酮组的心率(HR)、血氧饱和度(SpO2)和动脉压(MAP)值在麻醉诱导和切皮期分别与七氟醚组及复合组同一时期比较差异有统计学意义(P<0.05),HR和MAP值在术后比较差异有统计学意义(P<0.05),七氟醚组与复合组的HR、SpO2和MAP值在同一时期比较差异均无统计学意义(均P>0.05);氯胺酮组、七氟醚组、复合组患儿不良反应发生率渐次降低,三组数据比较差异有统计学意义(P<0.05)。结论:七氟醚复合小剂量舒芬太尼进行小儿腹股沟区手术的麻醉具有较理想的临床效果,不仅能够有效减少以往氯胺酮对患儿中枢神经的刺激与影响,同时可以有效降低麻醉诱导期及苏醒期的不良反应,适合临床推广应用。
Objective： To discuss the clinical effect of anesthesia with Sevoflurane combined with small doses of Sufentanil in children＇s groin area surgery.Methods： 96 children were randomly divided into three groups as Ketamine Group,Sevoflurane Group and Combined Group.Ketamine Group were intramusculared anesthesia with 5 mg/kg Ketamine,Sevoflurane Group inhaled Sevoflurane by face mask,and based on the method of Sevoflurane Group,Combined Group were intravenous injected with Sufentanil.Results： The HR,SpO2 and MAP of Ketamine Group had significantly differences with Sevoflurane Group and Combined Group in induction of anesthesia and skin incision period（P0.05）.The HR and MAP of Ketamine Group had significantly differences with Sevoflurane Group and Combined Group after surgery（P0.05）.The HR,SpO2 and MAP of Sevoflurane Group and Combined Group had no significantly difference in each period（all P0.05）.The adverse reaction rates had significantly difference in three groups（P0.05）.Conclusion： The anesthesia with Sevoflurane combined with small doses of Sufentanil in children＇s groin area surgery has better clinical results.The anesthesia method can reduce the stimulation of Ketamine on central nervous system and influence of children,and reduce the induction of anesthesia and the emergence of adverse reactions.
出处
《中国医药导报》
CAS
2011年第16期94-95,共2页
China Medical Herald
关键词
小儿腹股沟区手术
麻醉
七氟醚
舒芬太尼
氯胺酮
Groin area surgery in children
Anesthesia
Sevoflurane
Sufentanil
Ketamine
