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醋酸奥曲肽治疗恶性肠梗阻的疗效观察 被引量:5

Therapeutic Observation of Octreotide in Treatment of Malignant Bowel Obstruction
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摘要 目的:探讨奥曲肽治疗恶性肠梗阻的疗效。方法:将48例无手术适应证的恶性肠梗阻患者随机分为25例奥曲肽组和23例对照组,两组均给予常规禁食、胃肠减压、补液及纠正水电解酸碱紊乱的治疗。奥曲肽组,在常规治疗基础上加用奥曲肽(力尔宁)0.2 mg,皮下注射,每6 h或8 h1次,连用3~14 d。结果:奥曲肽组的症状缓解率为80%,平均肛门排气时间为4.7 d,副反应发生率为12%;对照组症状缓解率为27%,平均肛门排气时间为7 d,副反应发生率为43.5%。结论:奥曲肽治疗恶性肠梗阻效果满意,且早期可逆转肠梗阻。 Objective:To investigate the effect of octreotide in treatment of malignant bowel obstruction.Methods:Forty-eight patients with malignant bowel obstruction without surgical indication were randomly divided into an octreotide group(n=25) and a control group(n=23).The two groups were treated with traditional treatment of fasting,gastrointestinal decompression,supplementing fluid and correcting water electrolysis balance.Based on the traditional treatment,the octreotide group was injected octreotide 0.2 mg hypodermically(once every 6 h or 8 h) for 3 to 14 days continually.Results:The symptom remission rate in the octreotide group was 80%,the average anal exhaust time was 4.7 days and the incidence of side effect was 12 %.The symptom remission rate in the control group was 27%,the average anal exhaust time was 7 days and the incidence of side effect was 43.5%.Conclusion:The effect of octreotide is content in treatment of malignant bowel obstruction and it could reverse bowel obstruction in the early stage of malignant bowel obstruction.
作者 戴鹏
机构地区 山西省肿瘤医院
出处 《山西职工医学院学报》 CAS 2011年第2期9-11,共3页 Journal of Shanxi Medical College for Continuing Education
关键词 醋酸奥曲肽 恶性肠梗阻 治疗 octreotide malignant bowel obstruction treatment
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参考文献5

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同被引文献47

  • 1宋景贵,毕洁亮,肖正英.莪术油腹腔灌注防治术后粘连性肠梗阻的临床研究[J].山东中医药大学学报,2004,28(6):432-435. 被引量:9
  • 2彭宝岗,梁力建,胡文杰,王捷,黄敏菁,郑凯,张卓军,李威,温思奇.生长抑素治疗肠梗阻的临床研究[J].中华胃肠外科杂志,2004,7(6):474-476. 被引量:72
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