摘要
目的建立真实的人体颅腔三维模型,通过有限元方法分析人体颅腔随颅内压(ICP)变化的应变规律。方法以1例成年健康男性的颅腔CT扫描图像为基础,利用逆向工程软件Mimics 13.0建立人体颅腔三维模型,并通过ANSYS软件模拟临床ICP变化范围2.0～6.0kPa,分析三维颅腔表面的变形情况。结果利用Mimics软件建立了与真实人体颅腔几何结构和材料属性均高度相似的三维颅腔有限元模型,该模型相较于其他简化模型和普通计算机辅助设计(CAD)建模软件建立的模型具有细节更逼真、材料属性更贴切的特点,更具有普遍应用的价值。而且通过ANSYS有限元模拟分析,随着ICP的增高,颅腔表面应变呈上升趋势,在2.0～6.0kPa ICP变化范围内,颅腔表面应变范围为1.27～3.67με。随ICP变化,人体颅腔表面的应变规律和范围与前期研究的计算结果基本一致。结论建立的真实人体颅腔三维模型和模拟颅腔随ICP变化的变形规律具有较高的可信度,为临床研究颅腔变形提供了可靠的数据依据。
Objective To reconstruct a three-dimensional（3D） model of real human cranial cavity and exploit the deformation rule of cranial cavity with changing intracranial pressure（ICP） by finite element method. Methods Based on the cranial cavity CT images of a healthy adult male, the 3D model of human cranial cavity was constructed using Mimics 13.0 software. The strain and deformation regularity of the real human cranial cavity were analyzed using finite element software ANSYS to simulate the changing ICP. Results The 3D finite element model of cranial cavity was reconstructed, which had high similarity to the real human cranial cavity in terms of geometric and material properties. Compared with the ideal simplified model of cranial cavity or the models constructed by general computer aided design（CAD） software, the model of cranial cavity was more accurate and of more universal application value. Moreover, the strains of cranial cavity ranged from 1.27 to 3.67 ~ while ICP ranged from 2 to 6 kPa. The strain regularity and scope were consistent with the pre-simulated results. Conclusion It is demonstrated that the real 3D model of human cranial cavity and deformation rule with changing ICP had higher reliability, and provided more reliable data basis for clinical research on cranial cavity deformation.
出处
《生物医学工程与临床》
CAS
2011年第3期199-204,共6页
Biomedical Engineering and Clinical Medicine
基金
国家自然科学基金资助(300800290)
关键词
颅腔模型
颅腔变形
MIMICS
颅内压
cranial cavity model
deformation of cranial cavity
Mimics
intracranial pressure.
