摘要
皮肌炎是一组亚急性或慢性起病、免疫介导的自身免疫性疾病,主要累及横纹肌,以淋巴细胞浸润为主的非化脓性炎症病变。其确切的病因尚不清楚,可能与免疫异常、感染、肿瘤、遗传等因素有关。近年来,有关免疫失调研究在皮肌炎发病机制中取得较大的进展,而新型抗体及易感基因与皮肌炎发病的相关性也有报道。
出处
《中国麻风皮肤病杂志》
2011年第5期336-338,共3页
China Journal of Leprosy and Skin Diseases
参考文献20
-
1Creus KK,De Paepe B,De Bleecker JL.Idiopathic inflammatory myopathies and the classical NF-kappaB complex:current insights and implications for therapy.Autoimmunity Reviews 2009; 8 (7):627-631.
-
2Gunawardena H,Betteridge ZE,McHugh NJ.Myositis-specific autoantibodies:their clinical and pathogenic significance in disease expression.Rheumatology (Oxford) 2009;48(6):607-612.
-
3De Paepe B,Creus KK,De Bleecker JL.Role of cytokines and chemokines in idiopathic inflammatory myopathies.Current Opinion Rheumatol 2009;21(6):610-616.
-
4Khanna S,Reed AM.Immunopathogenesis of juvenile dermatomyositts.Muscle Nerve 2010;41(5):581-592.
-
5Greenberg SA.Dermatomyositis and type 1 intefferons.Current Opinion Rheumatol 2010; 12(3):198-203.
-
6Grundtman C,Malmstrom V,Lundberg IE.Immune mechanisms in the pathogenesis of idiopathic inflammatory myopathies.Arthritis Res Ther 2007;9(2):208.
-
7Feldman BM,Rider LG,Reed AM,et al.Juvenile dermatomyositis and other idiopathic inflammatory myopathies of childhood.Lancet 2008;371(9631):2201-2212.
-
8Huber AM.Juvenile dermatomyositis:advances in pathogenesis,evaluation,and treatment.Paediatr Drugs 2009;11(6):361-374.
-
9Mamyrova G.Cytokine gene polymorphisms as risk and severity factors for juvenile dermatomyositis.Arthritis Rheum 2008; 58 (12):3941-3950.
-
10Chinoy H,Payne D.HLA-DPB1 associations differ between DRB1 * 03 positive anti-Jo-1 and anti-PM-Scl antibody positive idiopathic inflammatory myopathy.Rheumatology (Oxford)2009;48(10):1213-1217.
同被引文献17
-
1Reed AM, Emste F. The inflammatory milieu in idiopathic inflammatory myositis. Curr Rheumatol Rep, 2009,11 (4) :295 -301.
-
2Banica L, Besliu A, Pistol G, et al. Quantification and molecular char- acterization of regulatory T cells in connective tissue diseases[ J ]. Auto- immunity, 2009,42( 1 ) :41 -49.
-
3Sanner H, Gran JT, Sjaastad I, et ah Cumulative organ damage and prognostic factors in juvenile dermatomyositis : a cross - sectional study median 16.8 years after symptom onset[ J]. Rheumatology( Oxford), 2009,48 (12) : 1541 - 1547.
-
4Piccirillo CA. Regulatory T cells in health and disease[ J]. Cytokine, 2008,43 ( 3 ) :395 - 401.
-
5Manel N, Unntmaz D, Littman DR. The differentiation of human T(H) - 17 cells requires transforming growth factor - beta and induction of the nuclear receptor ROR gammat [ J 1. Nat Immunol, 2008,9 ( 6 ) : 641 - 649.
-
6Ishii W, Matsuda M, Shimojima Y, et al. Flow cutomeric analysis of lymphocyte subpopulations and Thl/Th2 balance in patients with poly- myositis and dermatomyositis [ J ]. Inter Med, 2008,47 ( 18 ) : 1593 - 1599.
-
7Alelaza M, Szegedi A, Antal - Szalmas P, et al. Altered cytokine ex- pression of peripheral blood lymphocytes in polymyosits and dematomysi- tis[J]. Ann Rheum Dis, 2005,64(10) :1485 - 1489.
-
8Marvi U,Chung L,Fiorentino DF.Clinical presentation and evaluation of dermatomyositis[J].Indian J Dermatol,2012,57(5):375-381.
-
9Girouard SD,Velez NF,Penson RT,et al.Panniculitis associated with dermatomyositis and recurrent ovarian cancer[J].Arch Dermatol,2012,148(6):740-744.
-
10郝伟丽,周晓鸿.免疫因素在特发性炎症性肌病中的作用机制[J].皮肤病与性病,2010,32(2):17-19. 被引量:2
二级引证文献2
-
1李晓云,钮含春,田恒创,王春艳,韩允,许春艳,王晓军.皮肌炎中医证型与调节性T淋巴细胞的相关性[J].中国皮肤性病学杂志,2017,31(2):209-212.
-
2董英豪,杨灿,段振忠.皮肌炎患者外周血TH17 Treg细胞的表达水平及与疾病活动度的关系[J].安徽医学,2019,40(5):566-569. 被引量:3
-
1蔡卫民,张立煌.日本血吸虫病肝纤维化患者免疫失调有关因素的探讨[J].中华传染病杂志,1993,11(2):63-67. 被引量:22
-
2李俐,夏世勤,倪凤,刘开燕.84例老年人胰岛素抗体探讨[J].贵阳医学院学报,2003,28(3):224-226.
-
3张晓,陈顺乐.性激素雌激素受体与红斑狼疮的免疫失调[J].国外医学(免疫学分册),1991,14(3):138-141. 被引量:2
-
4富琦,陈信义.特发性血小板减少性紫癜与细胞免疫失调[J].医学信息(医学与计算机应用),2002,15(12):720-722. 被引量:4
-
5美科学家发现能抑制HIV的新型抗体[J].中国医药导报,2008,5(31):3-3.
-
6雷贤英,李雨昕.ICU免疫功能失调脓毒症患者血清降钙素原监测价值[J].国际医药卫生导报,2015,21(23):3437-3439. 被引量:3
-
7李荣芬.狼疮性肾炎的诊治进展[J].河北医药,2006,28(1):61-62. 被引量:3
-
8闫晓燕,逯春洁,高晓增,张俊玲,韩秀红,冯玉钰,王彬,杨广遂.川崎病急性期患儿外周血CD4^+CD25^+Foxp3^+T细胞水平的改变及其临床意义[J].中国煤炭工业医学杂志,2013,16(1):48-50. 被引量:2
-
9李詝,高金明.支气管扩张症发病机制及治疗进展[J].国际呼吸杂志,2013,33(8):627-631. 被引量:4
-
10董恂玮,赵玉平,郑以州,张凤奎,杨仁池.19例儿童及青少年Evans综合征回顾性临床分析[J].临床血液学杂志,2011,24(1):28-29. 被引量:6