摘要
目的 观察内镜下治疗和生长抑素（ Ｓ Ｓ）联合对食管静脉曲张出血的短期止血效果。方法 病人分二组， Ｓ Ｓ组在急诊内镜前后连续用 Ｓ Ｓ ５ 天；联合组在 Ｓ Ｓ基础上加行内镜下硬化剂或套扎，但内镜４８ 小时后停用 Ｓ Ｓ。结果 硬化剂３７ 例和套扎３２ 例共计６９ 例的联合组与６４ 例 Ｓ Ｓ组间具可比性。在需气囊压迫、最初止血率、再出血率和死亡率方面，联合组的效果显著优于 Ｓ Ｓ组。二组间的输出血量差异不显著。结论 与单纯 Ｓ Ｓ治疗相比，内镜治疗和 Ｓ Ｓ联合可减少气囊压迫的需求，提高止血率，降低再出血率，进而降低死亡率。
Objective The early effect of using somatostation(SS) alone was compared with that associated with endoscopic intervention for bleeding from esophageal varices(EV).Methods 133 patients with liver cirrhosis and EV bleeding were assigned to use of SS alone(n=64), 250 μg bolus injection and 250μg/h i.v. infusion for 5 days and to the endoscopic sclerosis(n=37) or band ligation(n=32) followed by 250μg/h i.v.dripping of SS for 2 days.Results It showed that patients receiving sclerotic injection and band ligation had better results in immediate hemostasis ,less tamponade assistance as well as lower rebleeding and mortality rates.No difference was found in amount of blood transfusion between the two therapies.Conclusion The combination of SS and endoscopic intervention justified its preference to the single application of SS.
出处
《中华消化内镜杂志》
1999年第4期213-215,共3页
Chinese Journal of Digestive Endoscopy
关键词
食管静脉曲张
出血
生长抑素
内窥镜
套扎术
Variceal bleeding Somatostatin Sclerotherapy Endoscopic ligation
