摘要
目的探讨睡眠时间与肥胖发生风险的关系。方法2004年7月采用多阶段分层随机整群抽样方法对南京市3个城区和1个郊县社区里常住的35岁以上居民进行基线调查，对其中非肥胖[体质指数（BMI）〈28kg／m^2]人群开展为期3年的随访，于2007年7-10月进行评估调查。采用多元线性回归和多元Logistic回归分析睡眠时间与罹患肥胖风险之间的关联。结果剔除基线调查时筛查出的肥胖人群（BMI≥28kg／m^2）后，样本人群为3936名，3年后共随访到2837名，随访率为72．1％。3年内新发生的肥胖患者为78人，累计发病率为2．7％。男女发病率（分别为2．3％和3．2％）差异无统计学意义。居民平均睡眠时间为7．2h，睡眠时间不足（〈7h／d）和过长（≥9h／d）的比例分别为25．4％和7．3％。与睡眠时间为8h／d相比，睡眠时间不足罹患肥胖风险是其约2倍，睡眠过长是其1．5倍；但睡眠不足差异有统计学意义（P〈0．05）；调整了年龄和其他协变量后，睡眠时间≤5h和6h者发生肥胖的风险仍显著高于8h／d者（调整RR值分别为2．382，95％CI：1．121～5．063；2．072，95％CI：1．064～4．035）；进一步调整基线腰围（WC）和臀围（HC），睡眠时间不足人群罹患肥胖风险有所降低，但差异仍有显著性（ρ〈0．05）。结论睡眠时间不足和过长均增加罹患肥胖的风险。睡眠时间可能是肥胖的危险因素之一。
Objective To examine the relationship between sleep duration and the risk of obesity in Nanjing residents. Methods Population-based cross-sectional study was conducted on local residents older than 35 years in three urban districts and one rural county in July 2004. The subjects who were non-obese （BMI〈28 kg/m^2） in the baseline survey were selected to investigate the follow-up survey in July 2007. Multiple linear regression and multivariate logistic regression analysis were used to estimate the incidence risk of obesity. Results Of 3 936 eligible subjects without obesity in baseline survey, 2 837 of them completed the 3dr follow-up survey, with a follow-up rate of 72.1%. There were 78 subjects diagnosed as obese patients, resulting in 2.7% of the three-year cumulative incidence of obesity, 2.3% in men and 3.2% in women. The mean sleep time was 7.2 hours per day, with 25.4% of subjects sleeping less than 7 hours per day and 7.3% sleeping 9 hours and more per day. Compared with those sleeping 8 hours per day, the adjusted relative risks for obesity was 2.382 （95%CI=1.121～5.063） for those with 5 hours or less of sleep and 2.072 （95%CI=1.064～4.035） for those with 6 hours of sleep, after adjustment for age and other eovariates. Further, after additional adjustment for baseline WC and HC, the positive association between short sleep duration and obesity was slightly attenuated but remained statistically significant. Conclusion The study provides evidence that both short and long sleep duration predict an increase risk of obesity. Sleep duration could be a risk factor for obesity.
出处
《中国慢性病预防与控制》
CAS
北大核心
2011年第3期226-229,共4页
Chinese Journal of Prevention and Control of Chronic Diseases
基金
江苏省社会发展规划资助项目(BS2002313)
南京市重点医学发展项目资助(ZKX0310)
关键词
肥胖
睡眠时间
随访研究
Obesity
Sleeping duration
Follow-up study
