摘要
目的:为探讨运动性血红蛋白低下时机体铁代谢、红细胞破坏与血红蛋白下降间的关系,为运动性血红蛋白低下的发生机制及预防提供依据。方法:随机选取广州体育学院体育教育系学生30人,男女各15人,进行起始负荷为60%最大心率强度,每周强度递增10%的跑步运动,5d/周,4周后测试受试者Hb、Ret、SF、Fer、sTfR和红细胞抗氧化指标MDA、SOD、CAT、GSH-px。结果:4周递增负荷跑步运动后受试者呈现运动性血红蛋白低下,血清铁蛋白持续性下降,转铁蛋白受体呈下降趋势或不变,但血清铁无明显变化;红细胞抗氧化酶的含量升高,脂质过氧化产物MDA呈持续增加趋势。结论:4周的递增负荷跑步运动中,红细胞自由基的生成增加及红细胞抗氧化能力的相对降低引起的红细胞破坏增加可能是运动性血红蛋白低下的发生原因,而不是由单纯缺铁所致。
Purpose： To research the relationship among iron metabolism,red blood cell destruction and hemoglobin decreasing during exercise-induced anemia,which provides a basis for the mechanism and prevention of exercise-induced anemia.Method： 30 students（male 15,female 15） were chose and taken increasing intensity running at 60%HRmax,increasing 10%HRmax every week.Four weeks later the blood Hb、Ret、SF、Fer、sTfR,and MDA、SOD、CAT、GSH-px of RBC were measured.Results： After 4 weeks increasing intensity running,Hb decreases significantly as exercise-induced anemia,and serum ferritin declining sustained,transferrin receptor,a downward trend or the same,but no significant change in serum iron;The levels of erythrocyte antioxidant enzymes were elevated,and lipid peroxidation MDA showed a tend of increasing.Conclusion： During the four weeks increasing intensity running,the increased free radicals and the lowered antioxidant capacity of red blood cell maybe the main reasons of exercise-induced anemia,rather than simply iron deficiency.
出处
《北京体育大学学报》
CSSCI
北大核心
2011年第5期52-54,59,共4页
Journal of Beijing Sport University
基金
国家科技部奥运攻关重点课题资助"提高运动员体能的关键技术"(课题编号:2002BA904B04-05)
国家科技进步二等奖
关键词
递增负荷
跑步运动
运动性血红蛋白低下
铁代谢
红细胞破坏
抗氧化酶
increasing intensity
running
exercise-induced anemia
iron metabolism
red blood cell destruction
antioxidant enzymes
