摘要
本文采用高效液相色谱法测定盐酸麻黄碱的含量，以苯巴比妥为内标，以磷酸二氢钾（００５ｍｏｌ／Ｌ）－甲醇（５３∶４７）为流动相，检测波长在２５７ｎｍ，在６０９４μｇ～３６５６６μｇ范围内有良好的线性关系，ｒ＝０９９９９，回收率为１００３３％（ｎ＝８），ＲＳＤ为１０％。
A HPLC method for the quantitative determination of Ephedrine Hydrochloride Tablet was described. The mobile phase is KH 2PO 4(0 05mol/L)-methanol(53∶47), detection wavelength is 257nm, and the internal standard is phenobarbital. The linear correlation was good in the range of 6 094～36 566μg of ephedrine hydrochloride (r=0 9999). The average recovery was 100 33%(n=8) and the relative standard deviation was 1 0%. The method is simple, rapid and accurate.
出处
《中国药事》
CAS
1999年第4期249-250,共2页
Chinese Pharmaceutical Affairs
