摘要
目的：探讨重症手足口病（Hand，footandmouthdisease，HFMD）的诊治经验。方法：依据临床表现及并发症将268例重症HFMD患儿分为重症及危重症两组，对其I脑床表现、病情动态变化、辅助检查、治疗及转归进行回顾性分析。结果：268例重症HFMD患儿，男159例（59．3％），女109例（40．7％）；年龄5个月～10岁，〈3岁者231例（86．2％），平均年龄2．9岁。I重症组，并发症以神经系统症状为主要表现者232例（86．6％），均存活，肠道病毒7l型（Enterovirus71，EV71）阳性135（58．2％）例；Ⅱ危重症组，并发神经、循环、呼吸等系统多器官损害者36例（13．4％），24例（8．95％）死亡，其中20例入院24h内死亡，EV71阳性28例。结论：HFMD重症危重型病情进展快，死亡率高，早期发现正确治疗是抢救成功的关键。
Objective： To investigate the diagnosis and treatment of severe hand, foot and mouth disease （ Hand, Foot and Mouth Disease, HFMD ）. Methods： According to clinical manifestations and comphcations,268 HFMD patients were divided into severe case group and critical case group, and then the clinical manifestations, illness dynamic changes, auxiliary examinations, treatments and prognoses were retrospectively analyzed. Resu/ts： Among the 268 severe HFMD infection patients, 159 were male patients （ 59.3% ）, and 109 were female patients （ 40.7% ）. The age of patient was from 5 months to 10 years old. Among them, younger than 3 years old patients were 231 cases （ 86.2% ） with an average age of 2.9 years old. In severe case group, complications in neurological system as main behavior were in 232 patients （ 86.6% ） ,who were ahve, and EV71 positive was in 135 （ 58.2% ）patients;In critical case group, multiple organ damages in nervous, circulatory, and respiratory system were in 36 cases （ 13.4% ）, and 24 cases （ 8.95% ）died, including 20 cases died within 24 h hospitalization, and EV71 positive was in 28 cases. Conclusion：HFMD severe critical type progresses fast, and with high mortality rate. An early discovery and correct treatment is the key to successful rescue.
出处
《重庆医科大学学报》
CAS
CSCD
北大核心
2011年第4期498-500,共3页
Journal of Chongqing Medical University
关键词
手足口病
重症
危重症
肠道病毒EV71
早期诊断
hand, foot and mouth disease （ HFMD ）
severe case
critical case
intestinal virus EV71
early diagnosis
