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RCAS1、Caspase-8在胃腺癌组织中的表达及意义 被引量:5

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摘要 目的探讨RCAS1、Caspase-8在胃腺癌组织中的表达及其意义。方法采用免疫组化SP法检测46例胃腺癌组织及其切端正常胃黏膜组织中RCAS1、Caspase-8的蛋白表达。结果正常胃黏膜组织及胃腺癌组织中RCAS1蛋白的阳性表达率分别为60.87%(28/46)和84.78%(39/46)(P<0.05)。正常胃黏膜组织及胃腺癌组织中Caspase-8蛋白的阳性表达率分别为80.43%(37/46)和65.22%(30/46)(P<0.05)。二者在胃癌组织中的表达呈负相关性(r=-0.321、P<0.05)。结论 RCAS1、Caspase-8蛋白在胃腺癌组织中的异常表达与胃腺癌的发生、发展有关。
作者 李晓芳
机构地区 河南省人民医院
出处 《山东医药》 CAS 北大核心 2011年第20期94-96,共3页 Shandong Medical Journal
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参考文献8

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