摘要
目的:探讨AMI后患者接受PCI治疗和常规药物治疗后BNP的表达与患者心室重构的关系。方法:选择2008年1月～2009年12月我院心内科收治的AMI病人,按照入选标准,将患者分为常规药物治疗组和直接PCI组。比较两组病人治疗前后的心功能分级积分、再次住院数、死亡数、血清BNP水平及治疗后1个月和(6～8)个月的LVDd(cm)、LVESV(mL)LVEF(%)。结果:直接PCI组较常规药物组的患者心功能分级积分明显提高(P<0.05)、再次住院数和死亡数明显减少(P<0.01),而常规药物组患者血清BNP水平较直接PCI组表达明显升高,对比有显著性差异(P<0.01);直接PCI组患者LVDd、LVESV、LVEF较常规药物组明显改善(P<0.01)。结论:BNP的表达对于AMI患者预后及心室重构情况具有重要的临床意义和预测价值。
Objective：Discussion the relationship between the BNP expression to the ventricular remodeling in AMI patients who received PCI treatment and conventional drug treatment Methods： The object of study selected the AMI patient who my hospital cardiovascular department in January, 2008 - December, 2009;The all patients are divided into conventional drug treatment group and PCI group according to the chosen standard.Compare of cardiac function in classification, the number of hospitalized again, the mortality, serum levels of BNP in the two groups of patients before and after the treatment. And to compare of the LVDd （cm）, LVESV （mL） of LVEF （%） in the two groups after 1 month and （6-8） months.Results：The cardiac function in classification in PCI group compared with the conventional drug group weree and the number of hospitalized again and the mortality in PCI group compared with the conventional drug group were decreased significantly.While BNP expression in conventional drug patients significantly increased in contrast to the expression of PCl Group,and there are have a significant differences.with the LVEF LVESV LVDd in PCI group were improved significantly in contrast to conventional drug group.Conclusion：The expression of BNP have an important clinical significance and predictive value.for left ventricular remodeling and prognosis in AMI patients.
出处
《中国医药导刊》
2011年第4期671-673,共3页
Chinese Journal of Medicinal Guide
关键词
急性心肌梗死
介入治疗
脑钠肽表达
心室重构
Acute myocardial infarction
Intervention
the expression of brain natriuretic peptide
Ventricular remodeling
