摘要
目的:分析中药结合介入方法治疗恶性梗阻性黄疸的疗效。方法:在PTCD或ENBD基础上加用中药治疗恶性梗阻性黄疽患者20例,观察其治疗前后血清总胆红素(TB)、结合胆红素(DB)、总胆汁酸(TBA)、碱性磷酸酶(ALP)、谷氨酰氨基转移酶(GGT)、丙氨酸转氨酶(ALT)及治疗后每日胆汁引流量并与单纯PTCD或ENBD组20例比较。结果:治疗后两组患者的TB、DB、TBA、ALP、GGT、ALT、ALP均明显下降;在降低TB、DB、GGT、TBA、ALT及增加每日胆汁引流量方面治疗组更为显著(P<0.05)。结论:中药能显著降低恶性梗阻性黄疸患者TB、DB、GGT、TBA、ALT水平。
Objective： To evaluate the clinical effect of interventional treatment and TCM on the treatment of malignant obstructive jaundice.Methods： A total of 30 patients with malignant obstructive jaundice were given TCM after PTCD or ENBD（the treatment group）.Of them,27 patients underwent PTCD or ENBD alone（the control group）.Blood samples were collected before and after the treatment.Serum concentrations of TB,DB,TBA,ALP,GGT,and ALT were measured.Clinical manifestation and daily bile flux were recorded and compared with the contro1 group.Comparisons were also made between pretreatment parameters and corresponding post treatment parameter.Results： Serum concentrations of TB,DB,TBA,ALP,GGT and ALT all significantly decreased in patients from both groups.Improvement in clinical manifestation was observed in both groups.The treatment group showed better effect in decreasing serum concentrations of TB,DB,GGT,TBA,ALT,and reducing daily bile flux（P0.05）.Conclusion： TCM was effective in decreasing serum TB,DB,GGT,TBA and ALT concentrations,alleviating symptoms and improving life quality.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2011年第6期1318-1320,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
关键词
中药
恶性梗阻性黄疸
介入治疗
TCM
Malignant obstructive jaundice
Interventional treatment
