摘要
目的观察全身热疗联合腹腔内灌注化疗治疗晚期胃肠道恶性肿瘤与全身静脉化疗的近期疗效和毒副反应。方法将我科2006年1月—2010年10月收治的晚期胃肠道恶性肿瘤患者36例,随机分为全身热疗联合腹腔内灌注化疗组(A组)和全身静脉化疗组(B组),治疗4周期后观察两组患者的近期疗效及毒副作用。结果近期疗效两组的有效率分别为:A组63.2%、B组17.6%,A组明显优于B组(P<0.05);毒副反应恶心、呕吐等消化道反应和骨髓抑制症状两组分别为:A组15.8%、B组64.7%,A组低于B组(P<0.05);腹痛腹胀症状,A组36.8%、B组5.9%,A组多于B组(P<0.05)。结论对晚期胃肠道恶性肿瘤,采用全身热疗联合腹腔内灌注化疗疗效确切、毒副作用轻,有利于提高患者生活质量。
Objective To observe the short-term curative effect and the adverse reaction of the body heat therapy combined celiac perfusion chemotherapy and the systemic venous chemotherapy in advanced malignant tumors of gastrointestinal.Methods 36 patients with advanced malignant tumors of gastrointestinal in our hospital from January 2006 to October 2010 were divided into two groups randomly,one group was treated by body heat therapy combined celiac perfusion chemotherapy（group A）,the other was treated by systemic venous chemotherapy（group B）.The short-term curative effect and the adverse reaction in the two groups were observed 4 weeks later.Results The effective rate in group A was 63.2% and in group B was 17.6%,it was obviously better in group A than in group B（P0.05）;the gastrointestinal reactions such as nausea and vomiting and the marrow inhibit symptoms were all 15.8% in group A and 64.7% in group B,it was obviously lower in group A than in group B（P0.05）;the abdominal pain abdominal distension symptoms was 36.8% in group A and 5.9% in group B,it was higher in group A than in group B（P0.05）.Conclusion It was much better to use the body heat therapy combined celiac perfusion chemotherapy in advanced malignant tumors of gastrointestinal and was propitious to improve the quality of life of the patients.
出处
《临床军医杂志》
CAS
2011年第3期477-479,共3页
Clinical Journal of Medical Officers
关键词
全身热疗联合腹腔灌注化疗
晚期胃肠道恶性肿瘤
疗效分析
body heat therapy combined celiac perfusion chemotherapy
advanced malignant tumors of gastrointestinal
efficacy analysis
