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瑞舒伐他汀对高血压合并高胆固醇血症患者左心功能及颈动脉粥样硬化的影响 被引量:6

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摘要 目的观察瑞舒伐他汀对原发性高血压合并高胆固醇血症患者左心功能及颈动脉粥样硬化的影响。方法 2009年1月至2010年6月期间,112例原发性高血压患者随机分为两组,观察组在常规治疗的基础上加用瑞舒伐他汀,比较观察两组的临床疗效及对患者左心功能及颈动脉粥样硬化的影响。结果观察组的总有效率为91.1%,明显高于对照组的75.0%,两组比较差异有统计学意义(P<0.05)。两组治疗前后LVEF和LVPER水平比较,差异均无统计学意义(P>0.05)。观察组治疗后LN和IMT水平均较治疗前明显下降,差异有统计学意义(P<0.05),并且治疗后观察组LN和IMT水平均明显低于同期对照组,差异有统计学意义(P<0.05)。而对照组治疗前后LN和IMT水平比较,差异无统计学意义(P>0.05)。结论瑞舒伐他汀对原发性高血压合并高胆固醇血症患者进行治疗能够明显提高临床疗效,改善颈动脉粥样硬化,但对患者左心功能影响不大。
出处 《心脑血管病防治》 2011年第3期213-214,共2页 CARDIO-CEREBROVASCULAR DISEASE PREVENTION AND TREATMENT
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  • 1刘力生.2004年中国高血压防治指南(实用本)[J].中华心血管病杂志,2004,32(12):1060-1064. 被引量:2620
  • 2Steven E. Nissen,Stephen J. Nicholls,Ilks Sipahi,Peter Libby,Joel S. Raichlen,Christie M. Ballantyne,Jean Davignon,Raimund Erbel,Jean Charles Fruchart,Jean-Claude Tardif,Paul Schoenhagen,Tim Crowe,Valerie Cain,Kathy Wolski,Marlene Coormastic,E. Murat Tuzcu,仝其广(译),王淑敏(译),胡大一(校).极高强度他汀治疗对冠状动脉粥样硬化消退的影响——ASTEROID试验[J].美国医学会杂志(中文版),2006,25(4):215-223. 被引量:346
  • 3周吴刚,吴士尧.血清HSP60对冠心病的诊断价值探讨[J].实用心脑肺血管病杂志,2006,14(5):360-361. 被引量:7
  • 4路岩,姜一农,崔海燕,张英.阿托伐他汀对血脂正常高血压患者血管内皮功能的影响[J].中华高血压杂志,2007,15(3):192-195. 被引量:44
  • 5Sesso B. The patients with high level of serum CRP have a higher risk incidence with EH [ J ] . JAMA, 2003, 290 : 2945-2950.
  • 6Magen E, Mishal J, Paskin J, et al. Resistant arterial hypertension is associated with higher blood levels of complement C3 and C-reactive protein [ J ] . J Clin Hypertens (Greenwich), 2008, 10 (9): 677-683.
  • 7Ridker PM. Silvertown JD. Inflammation, C-reactive protein, and atherothrombosis [ J ] . J Periodontol, 2008, 79 (8 Suppl) : 1544-1551.
  • 8Rouleau J. Improved outcome after acute coronary syndromes with an intensive versus standard lipid-lowering regimen: Results from the Pravastatin or Atrovastatin Evaluation and Infection Therapy-Thrombolysis in Myocardial Infarction 22 (PROVE IT-TIM 22) trail [ J ] . Am J Med, 2005, 118: 28-35.
  • 9Ridker PM, Danielson, Fonseca FA, et al. Justification for the use of statins in primary prevention: an intervention trial evaluating rosuvastatin. [ J ] . N Eng J Med, 2008, 359: 2195-2207.
  • 10Sesso B. The patients with high level of serum CRP have a higher risk incidence with EH [ J ]. JAMA, 2003, 290: 2945-2950.

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  • 1Steven E. Nissen,Stephen J. Nicholls,Ilks Sipahi,Peter Libby,Joel S. Raichlen,Christie M. Ballantyne,Jean Davignon,Raimund Erbel,Jean Charles Fruchart,Jean-Claude Tardif,Paul Schoenhagen,Tim Crowe,Valerie Cain,Kathy Wolski,Marlene Coormastic,E. Murat Tuzcu,仝其广(译),王淑敏(译),胡大一(校).极高强度他汀治疗对冠状动脉粥样硬化消退的影响——ASTEROID试验[J].美国医学会杂志(中文版),2006,25(4):215-223. 被引量:346
  • 2许顶立.高血压与脂质代谢紊乱[J].中华心血管病杂志,2006,34(9):861-864. 被引量:39
  • 3赵水平.降胆固醇防治心脑血管疾病的现状[J].中华内科杂志,2007,46(2):168-169. 被引量:16
  • 4Brett SJ, Simon J, Gibbs R, et al. Impairment of endothelium-de- pendent pulmonary vasodilation in patients with primary pulmonary hypertension [ J ]. Thorax, 1996,51 ( 1 ) :89 - 91.
  • 5Machino-Ohtsuka T,Seo Y,Ishizu T,et al. Combined assessment of carotid vulnerable plaque, renal insufficiency, eosinophilia, and hs - CRP for predicting risky aortic plaque of cholesterol crystal embol- ism[J]. Circ J,2010,74(1):51-58.
  • 6Katsiki N, Wierzbicki AS, Mikhailidis DP. Pulmonary arterial hy- pertension and statins : an update[ J]. Curr Opin Cardiol,2011,26 (4) :322 -326.
  • 7Ma T, Chang MH,Tien L, et al. The long-term effect of statins on the risk of new-onset diabetes mellitus in elderly Taiwan Residents patients with hypertension and dyslipidaemia:a retrospective longitudinal co- hort study[ J]. Drugs Aging,2012,29( 1 ) :45 - 51.
  • 8Scherer ML,Nalls MA,Pawlikowska L,et al. Admixture mapping of ankle-arm index: identification of a candidate locus associated with peripheral arterial disease [ J ]. J M ed G enet,2010,47 ( 1 ) : 1 - 7.
  • 9Igarashi Y, Chikamori T, Tomiyama H, et al. Clinical significance of inter-arm pressure difference and ankle-brachial pressure index in patients with suspected coronary artery disease [ J ]. J Cardiol,2007,50 ( 5 ) :281 - 289.
  • 10John R. Crouse Ⅲ,Joel S. Raichlen,Ward A. Riley,Gregory W. Evans,Mike K. Palmer,Daniel H. O' Leary,Diederick E. Grobbee,Michiel L. Bots,李军(译).瑞舒伐他汀对存在亚临床动脉粥样硬化的低危人群颈动脉内膜中层厚度进展的影响——METEOR试验[J].美国医学会杂志(中文版),2007,26(4):208-216. 被引量:45

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