摘要
目的观察健脾化痰通脉方对冠心病血脂异常患者临床症状及血脂水平的影响。方法将60例冠心病血脂异常患者随机分为治疗组和对照组各30例,在常规治疗的基础上,治疗组给予健脾化痰通脉方,每日一剂,分早晚两次温服;对照组给予辛伐他汀20 mg,于每晚睡前口服。疗程均为8周。疗程结束时比较两组中医症状积分变化及血清总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)等指标。结果健脾化痰通脉方能明显改善冠心病血脂异常患者胸闷、胸痛、气短、体胖多痰、身体困重等临床症状,与对照组比较差异有统计学意义(P<0.05或P<0.01);且能明显改善患者各项血脂指标(P<0.01),实验室指标总有效率为73.33%,与对照组比较疗效接近,差异无统计学意义(P>0.05)。结论健脾化痰通脉方能明显改善冠心病血脂异常患者临床症状及各项血脂指标,并具有较高的安全性。
Objective To observe the effect of Jianpi Huatantongmai recipe on coronary heart disease with abnormal blood lipid.Methods Sixty patients（pts） with coronary heart disease and abnormal blood lipid were randomly assigned to two groups： Treatment group（n=30） treated with Jianpi Huatantongmai recipe and control group（n=30） treated with simvastatin.All pts were received routine treatment.Main symptoms,total cholesterol（TC）,triglyceride（TG）,low density lipoprotein-cholesterol（LDL-C） and high density lipoprotein-cholesterol（HDL-C） were studied and compared.Results Jianpi Huatantongmai recipe could significantly improve clinical symptoms,such as the sense of suppression in the chest,pain in the chest,short of breath,sputum and sleepy,compared with that in the control group（P0.05 or P0.01）.The Recipe could improve the abnormal blood lipid（P0.01）.The total effective rate in treatment was 73.33%,and it was close to that of simvastatin（P0.05）.Conclusion Jianpi Huatantongmai recipe could improve the symptoms of coronary heart disease and abnormal blood lipid.
出处
《中西医结合心脑血管病杂志》
2011年第6期647-649,共3页
Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
关键词
冠心病
血脂异常
健脾化痰通脉方
coronary heart disease abnormal blood lipid Jianpi Huatantongmai recipe
