摘要
目的探讨内镜胆道支架置入术(EBMSD)联合鼻胆管引流术(ENBD)姑息性治疗恶性梗阻性黄疸(MOJ)的疗效。方法对44例MOJ患者应用EBMSD联合ENBD,观察其疗效、并发症及生存率。结果 44例患者中置管成功率为93.18%(41/44),其中塑料支架置入29例,金属支架置入12例;支架置入后黄疸消退的总有效率为95.1%,且术后1周肝功能各指标较术前有显著改善,差异有统计学意义(P<0.05);术后并发症4例,其中血尿淀粉酶升高2例,血常规示轻度升高1例,急性胰腺炎1例;金属支架组1个月、3个月及6个月生存率分别为100.0%、83.3%和58.3%,塑料支架组1个月、3个月及6个月生存率分别为89.7%、65.5%和31.0%,两组比较差异具有统计学意义(P<0.05)。结论 EBMSD联合ENBD治疗MOJ疗效确切,可祛除黄疸、提高生存质量,是一种安全有效的姑息性治疗手段。
Objective To explore the effect of endoscopic biliay metal stent drainage （EBMSD） combined with endoscopic naso-biliary drainage（ ENBD ）for the treatment of malignant obstructive jaundice（MOJ）. Methods 44 patients with MOJ were treated by EBMSD and ENBD. The clinical data for the patients were reviewed and analyzed. Results 41 out of the 44 （93.18%） were successfully underwent EBMSD and ENBD,including 36 metal stents and 18 plastic stents. The effective rate of jaundice fadeaway was 95.1% after stents placement,and the indicators of liver function was improved significantly compared with the preoperative conditions （P〈0.05）. Four cases had complications,but none of them had sequela after correct treatment. The survival rates of 1 month,3 months and 6 months after the treatment were 100.0%,83.3% and 58.3% for metal stents,89.7%,65.5% and 31.0% for plastic stents. there were significantly difference （P〈0.05）. Conclusion EBMSD and ENBD applied on treatment of MOJ can remove jaundice and improve quality of life,this method is a safe and effective palliative treatment.
出处
《中国现代医生》
2011年第18期243-245,共3页
China Modern Doctor
关键词
内镜胆道支架置入术
鼻胆管引流术
恶性梗阻性黄疸
Endoscopic biliay metal stem drainage
Endoscopic naso--biliary drainage
Malignant obstructive jaundice
