摘要
目的探讨2型糖尿病患者糖尿病足发病的危险因素,尤其是独立的危险因素。方法 选取163例2型糖尿病患者,其中糖尿病足63例(DF组),非糖尿病足100例(NDF组),回顾性分析两组患者的临床资料及并发症发生情况,采用Logistic回归分析筛选糖尿病足的危险因素。结果两组患者的体质指数(BMI)、纤维蛋白原(FIB)、高密度脂蛋白胆固醇(HDL-C)、糖化血红蛋白(HbA1c)、收缩压(SBP)水平以及并发症(周围神经病变、外周动脉粥样硬化闭塞症)发生率比较,差异均有统计学意义(P<0.05)。Logistic回归分析表明,FIB、SBP、外周动脉粥样硬化闭塞症和糖尿病视网膜病变是2型糖尿病发生糖尿病足的独立危险因素。结论严格长期控制血糖及调节血压、血脂、FIB的失衡,积极治疗糖尿病各种慢性并发症,能预防糖尿病足的发生。
Objective To analyze the risk factors of diabetic foot in patients with type 2 diabetes mellitus（T2DM）. Methods Clinical data and occurrences were analyzed retrospectively in 163 T2DM patients who were divided into groups diabetic foot（DF,n=63）,non-diabetic foot（NDF,n=100）.The risk factors of DF were analyzed by Logistic regression method. Results There was significant difference between 2 groups in BMI,fibrinogen（FIB）,high density lipoprotein cholesterol（HDL-C）,glycosylated hemoglobin A1（HbA1c）,systolic blood pressure（SBP） levels and complications such as peripheral neuropathy,peripheral atherosclerosis（P〈0.05）.Logistic regression analysis showed that FIB,SBP,arteriosclerosis obliterans and diabetic retinopathy were independent risk factors of DF in T2DM patients. Conclusion DF can be prevented by controlling blood glucose strictly and in a long term,by regulating the balance of blood pressure,lipid and FIB imbalance and by treating the chronic diabetic complications.
出处
《中国全科医学》
CAS
CSCD
北大核心
2011年第15期1629-1631,1634,共4页
Chinese General Practice
