摘要
目的探讨C反应蛋白(CRP)和D-二聚体(D-D)在患者外科手术后病情监测中的应用。方法对照组30例,实验组85例,对照组于健康体检时和实验组分别于患者手术前及手术后1、3、7 d测定血清CRP和D-D的浓度。结果对照组和实验组手术前的血清CRP、D-D浓度比较差异无统计学意义(P>0.05)。实验组术后和术前血清CRP、D-D浓度比较差异有统计学意义(P<0.01)。无并发症的患者术后3 d的血清CRP、D-D浓度逐步下降至正常;术后伴有并发症的患者直至7 d后的血清CRP、D-D浓度仍然升高,有、无并发症的患者血清CRP、D-D浓度比较差异有统计学意义(P<0.01)。结论术后检测血清CRP、D-D浓度有助于患者感染、深静脉血栓、弥散性血管内凝血(DIC)等并发症的监测。
Objective To evaluate the application of C reactive protein （CRP） and D-dimer （I〉D） in the post-surgical monito ring of pathogenetic condition. Methods 30 healthy individuals （control group） and 85 patients （experimental group） were enrolled. Serum concentration of CRP and D-D were detected for control group, and before, 1,3 and 7 days after surgery for experimental group. Results There were no statistical differences of serum concentration of CRP and D-D between the results of control group and experimental group detected before surgery（P〈0.05）. There were statistical differences of serum concentration of CRP and D-D between the results of experiment group detected before and after surgery （P〈0.01）. Serum concentration of CRP and D-D gradually decreased to normal levels in patients without complications 3 days after surgery, but still increased in patients with complications 7 days after surgery,and there were statistical differences of serum concentration of CRP and IT, D between patients with and without complications （P〈0.01）. Conclusion Detection of serum concentration of CRP and D-D could be helpful for the monitoring of complications such as infection,deep venous thrombosis and DIC after surgery.
出处
《国际检验医学杂志》
CAS
2011年第8期873-874,共2页
International Journal of Laboratory Medicine
