摘要
目的:对比分析急性心肌梗死(AMI)相关动脉和稳定性心绞痛(SAP)罪犯病变的虚拟组织学特点,以期早期识别易损斑块。方法:对63例急性ST段抬高性心肌梗死患者行直接介入治疗,随机选取同期介入治疗的63例SAP患者做对照。完成冠状动脉造影之后,对罪犯病变进行血管内超声检查,保存普通灰阶图像和虚拟组织学超声数据。分析斑块的虚拟组织学特点。结果:两组患者年龄、性别、高血压、吸烟、糖尿病、高脂血症等临床资料差异无统计学意义,SAP组和AMI组虚拟组织学血管内超声特点不同,AMI组纤维脂质成份和坏死组织明显增多,钙化成份少。两组的坏死组织/钙化组织面积比值分别是3.26±1.64比7.81±2.66,差异最显著(P<0.01)。结论:AMI相关动脉的斑块虚拟组织学有其自身特点,据此早期识别易损斑块,对降低AMI的发病率大有裨益。
Objective： To analyze the characteristic of visual histology-intravenous ultrasound（VH-IVUS） in 63 patients with ST segment elevated type acute myocardial infarction（AMI） and reveal the difference of VH-IVUS between stable angina patients and AMI.Methods： Those 63 patients with ST segment elevated AMI who reiceived direct percutaneous coronary artery intervention,other 63 patients with stable angina who also reiceived PCI selected as control group.After completing coronary artery graphy,IVUS examination was done in culprit grayscale and VH data were stored.VH-IVUS parameters of atheroma plaque were analyzed.Results：The difference among Age,gender,hypertension,smoking,diabetes mellitus and hyperlipidemia was not statistically significant,but the characteristic of VH-IVUS was different.In the atheroma plaque of AMI there were more fibro-fatty tissue and necrotic tissue,less dense calcium,ratio of necro tissue area/calcific density was 3.26±1.64 VS 7.81±2.66（P0.01）.Conclusion：The characteristic of VH-IVUS in AMI patients is obvious,earlier detecting vulnerable atheroma plaque through VH-IVUS is helpful to decreasing the incidence of AMI.
出处
《天津医科大学学报》
2011年第2期210-211,214,共3页
Journal of Tianjin Medical University
基金
学院科研基金面上项目(WY200811)
关键词
心肌梗死
血管内超声
虚拟组织学
Acute myocardial infarction
Intravenous ultrasound
Visual histology
