摘要
目的随着现代新生儿医学的发展,机械通气的广泛应用,新生儿呼吸机相关性肺炎(ventilator-associated pneumonia,VAP)已成为新生儿重症监护病房(NICU)备受关注的话题,本文重点分析和探讨亳州市人民医院新生儿呼吸机相关性肺炎(VAP)的发生情况、病原菌的种类、药敏监测及耐药性情况,为积极有效预防和治疗VAP提供一定的理论依据。方法回顾性分析118例机械通气超过48 h新生儿中符合VAP诊断标准的43例患儿,行下呼吸道分泌物及撤机时气管导管末端做细菌培养和药物敏感实验。结果 118例进行机械通气的患儿有43例发生了VAP,发生率36.44%,其中39例痰培养检测阳性。结论 VAP的发生率与插管次数、机械通气时间、胎龄、原发性肺部疾病等呈正相关,应针对性的对VAP患儿监控,并根据病原学结果合理用药。
Objective With the development of modern neonatal medicine,the extensive application of mechanical ventilation,neonatal ventilator-associated pneumonia（ventilator-associated pneumonia VAP） had become a neonatal intensive care unit（NICU） topic of concern,the paper was to analyze and discuss key hospital neonatal ventilator-associated pneumonia（VAP） incidence,the types of pathogens,drug resistance surveillance and drug resistance,as positive and effective prevention and treatment of VAP to provide a theoretical basis.Methods A total of 118 patients from September 2008 to August 2010 among more than 48 hours of mechanical ventilation in neonates met diagnostic criteria for VAP of 43 children underwent lower respiratory tract secretions and weaning the end of the end tracheal tube for bacterial culture and drug sensitivity tests were retrospectively analyzed.Results 118 cases of children with mechanical ventilation,43 patients had VAP,the incidence was 36.44% in which 39 patients with positive sputum culture.Conclusion VAP children should be monitored targetedly,and rational drug use should be performed according to the etiology.
出处
《中华全科医学》
2011年第7期1071-1071,1113,共2页
Chinese Journal of General Practice
关键词
机械通气
呼吸机相关性肺炎
病原学监测
Mechanical ventilation
Ventilator-associated pneumonia
Pathogen monitoring
