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登革病毒包膜E蛋白III区 被引量：3

Dengue virus envelope protein domain Ⅲ
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摘要 登革病毒包膜E蛋白III区(DENV ED3)是登革病毒与敏感细胞受体结合的功能区域,对其结构和功能的研究,将有助于理解登革病毒与其敏感细胞间的相互作用和致病机理,为登革病毒受体研究和研发特异性阻断剂控制DENV感染奠定基础。现就DENV ED3的研究进展作一综述。 Dengue virus envelope protein domain Ⅲ（DENV ED3） is the functional area of Dengue virus to combine with sensitive cell receptor.Researching the structure and function of DENV ED3 contributes to the understanding of the interaction of dengue virus with sensitive cells and the viral pathogenesis,which also helps lay foundation for investigating the dengue virus receptors and developing the specific blocking agent to control DENV infection.Here we reviewed the recent advancement in study of DENV ED3.
作者 杨杰 饶贤才
机构地区 第三军医大学基础医学部微生物学教研室重庆市微生物工程重点实验室
出处 《生命的化学》 CAS CSCD 北大核心 2011年第3期366-371,共6页 Chemistry of Life
基金 国家自然科学基金(31070811) 校回国启动基金(NO.2009XHG03) 校预研基金(NO.2009XYY04) 重庆市自然科学基金(启动基金)(CSTC 2009BB5015)资助
关键词 DENVED3 病毒受体 膜融合 病毒毒力 DENV ED3 virus receptors membrane fusion virus virulence
分类号 R373 [医药卫生—病原生物学]
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参考文献24

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二级参考文献22

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生命的化学
2011年 第3期

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