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女性泌尿生殖道支原体感染状况及药敏试验分析

Results of Ureaplasma urealyticum and Mycoplasma hominis infection in female urogenital tract and drug sensitivity test
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摘要 目的了解本地区近年来引起泌尿生殖道炎症中解脲支原体(Uu)、人型支原体(Mh)感染情况以及Uu、Mh对药物的敏感率,以例指导临床合理用药。方法采用支原体培养、鉴定、药敏一体化试剂盒对238例女性泌尿生殖道感染患者的样本进行检测,并对药敏结果进行统计分析。结果 238例患者中,88例支原体检测阳性,总阳性率为36.97%;其中单纯Uu阳性率为23.95%,单纯Mh阳性率为2.94%,Uu、Mh混合阳性率为10.08%。Uu对强力霉素和美满霉素的敏感率最高,均为98.25%,对交沙霉素和罗红霉素次之,均为92.98%;Mh敏感率最高的是美满霉素,为100%,其次为强力霉素、交沙霉素和甲砜霉素,均为85.71%;Uu和Mh混合感染者,敏感率最高的是美满霉素,为87.50%,强力霉素和交沙霉素次之,分别为83.33%和70.83%。结论在女性泌尿生殖道炎症中,支原体检测的阳性率较高,对于单纯Uu感染者用药首选强力霉素或美满霉素,单纯Mh感染率者首选美满霉素;对Uu和Mh混合感染者首选美满霉素,强力霉素、交沙霉素次之。 Ahn To understand the status of Ureaplasma urealyticum and Mycoplasma hominis infection in female urogential tract and their usceptibility to antibiotics in inJingzhou area. Methods Ureaplasma urealyticum and Mycoplasma hominis from 238 femal urogenital tract were cultured and identified,then drug susceptibility tests were conducted and the results were analyzed. Results Out of the 238 females 88 (36.97%) were positive including 23.95% of them were positive for Ureaplasma urealyticum,2.94% were positive for Mycoplasma hominis ,and 10.08% were mined infections. The susceptibility of Ureaplasma urealyticum to doxycycle and mincycline were all as high as 98.25% ,followed by josamycine oxithromycin ,all 92.98%; while the susceptibility of Mycoplasma hominis mincycline was 100% ,followed by doxycycline,josamycine,thiamphenine,all were 85.71%. In the mixed infections Us and Mh were highly susceptible to mincyeline (87.50%),followed by doxycycline and josamycine (83.33% and 70.83%). Conclusion The positive rates of Us and Uh infection in female urogenital tract is high and drug susceptibility tests should be performed to offer scientific guidance for clinical rational use of antibiotics.
作者 易光明
出处 《中国热带医学》 CAS 2011年第6期746-747,共2页 China Tropical Medicine
关键词 女性泌尿生殖道 支原体 药敏试验 Female urogenital tract Mycoplasma Drug susceptibility test
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