摘要
Survivin基因是迄今为止发现的最强的凋亡抑制因子(IAP)。近期发现Survivin基因启动子多态性与肿瘤的发病风险和遗传易感性密切相关,可以为进一步揭示肿瘤的发病风险与基因多态性的相关性,以及肿瘤基因诊断和预防筛选提供线索。
Survivin gene is the strongest inhibitor of apoptosis so far. Recently, it was found that the promoter polymorphism of survivin gene is closely related to risk of cancer and genetic susceptibility. This finding might provide clues for further elucidation of the correlation of risk of cancer and genetic polymorphism, and for diagnosis, prevention and screening of cancer gene.
出处
《国际肿瘤学杂志》
CAS
2011年第6期409-411,共3页
Journal of International Oncology
基金
基金项目:云南省科技计划基金资助项目(2007C0025R)