摘要
目的:观察白芍总苷治疗寻常性银屑病的疗效及不良反应。方法:采用随机对照临床试验。90例符合纳入标准的患者随机分为3组。治疗组30例及对照组60例,分别使用白芍总苷1.8 g/d加5%松馏油软膏(A组)、5%松馏油软膏加海棠合剂(B组)及单用5%松馏油软膏(C组)。疗程均为6周。治疗前、后检查3组患者的血、尿、粪常规及肝、肾功能,同时观察患者的不良反应。结果:A组有效率为83.3%,B组及C组分别为86.7%、46.7%。A组和B组有效率差异无统计学意义(P>0.05);而A、B组分别与C组比较有效率差异均有统计学意义(P<0.05)。3组的不良反应均较少。结论:白芍总苷联合5%松馏油软膏治疗寻常性银屑病疗效明显,且不良反应少,安全性高。
Objective： To observe the therapeutic effect and adverse reactions of total glucosides of paeony capsules （TGP） in treatment of psoriasis vulgaris. Methods： A randomized controlled clinical trial was conducted. Ninety patients were random- ized into the treatment group （n=30） and two control groups （n=60）. The treatment group was treated with TGP and 5% pine tar （Group A）. Control groups were ＇respectively treated with 5% pine tar （Group C） and additionally begonia mixtures （Group B）. Blood routine, stool and urine routine, liver and kidney function in all patients were detected before and after 6 weeks treatment. In addition, adverse reactions were monitored. Results： The response rate was 83.3% for group A and 86.7%, 46.7% for control group B and C. There was no significant difference between group A and B （P〉 0.05）, but significant differ- ence （P〈 0.05） in group A and group B compared to group C. Adverse reactions of all groups were rare. Conclusions： TGP combined with 5% pine tar have significant effects on psoriasis vulgaris with fewer side effects and good safety.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2011年第7期433-435,共3页
Journal of Clinical Dermatology
关键词
白芍总苷
银屑病
海棠合剂
TGP
psoriasis vulgaris
begonia mixtures
