摘要
美国科学家关于内源性气体分子一氧化氮（NO）和一氧化碳（CO）生物学效应的研究开创了生命调节的新理论。我们近年来提出在心血管功能调节中还存在第三个气体信号分子硫化氢（H2S）[1-4],这推进了生命科学领域科学研究的进步。
The endogenous cardiovascular generation, physiological and pathophysiological effects of SO2 on cardiovascular diseases have been recently studied. It has been demonstrated that SO2 plays important physiological and pathophysiological roles in relaxing blood vessels, inhibiting cardiac function, improving vascular remodeling, inhibiting inflammation, anti-oxidation, and regulating lipid metabolism; thus playing a significant role in the pathogenesis of pulmonary hypertension, systemic, hypertension, myocardial ischemia-reperfusion injury and acute lung injury, etc. SO2 may be a novel gasotransmitter which plays an important role in mammals.
出处
《北京大学学报（医学版）》
CAS
CSCD
北大核心
2011年第3期481-484,F0003,共5页
Journal of Peking University:Health Sciences
基金
国家重点基础研究发展规划项目基金(2006CB503807)
教育部博士点基金(20070001702)
国家长江学者奖励计划
国家自然科学基金(7093136)资助~~
关键词
二氧化硫
心血管系统
生物学
Sulfur dioxide
Cardiovascular system
Biology
