摘要
目的：本研究制订中药黄连结肠靶向制剂的质量标准。方法：采用TLC法鉴别黄连;采用HPLC法测定盐酸小檗碱含量。结果：在TLC色谱中能检出盐酸小檗碱,在HPLC色谱中测定盐酸小檗碱在20.00~100.00μg/mL范围内呈良好线性关系（r=0.99989）,平均回收率为100.22%,RSD为1.85%。结论：定性定量方法简便准确,能有效控制中药黄连结肠靶向制剂的质量。
Objective：To establish the quality standards of Berberine Hydrocholride colon-specific targeting coated tablets.Methods：Huanglian was indentified by TLC,and Berberine Hydrocholride was determined by HPLC.Berberine Hydrocholride could be detected by TLC.Result：Berberine Hydrocholride had a good liner relationshipin the range of 1.00～40.00μg/mL（r =0.99989）.The average recovery was 100.22%with RSD of 1.85%.Conclution：The method is simple and accurates with a strong specificity,and can be used for quality control of Berberine Hydrocholride colon-specific targeting coated tablets.
出处
《牡丹江医学院学报》
2011年第3期16-19,共4页
Journal of Mudanjiang Medical University
关键词
结肠靶向
盐酸小檗碱
质量标准
Colon targeting
Ulcerative
Berberine Hydrocholride
Qualitystandards
