摘要
目的探讨激光光凝术治疗糖尿病视网膜病变（DR）的临床疗效及其影响因素。方法选择我院收治的DR患者186例324眼作为研究对象,均进行视网膜激光光凝治疗,术后随访4~24个月（平均16.2个月）。结果 324眼中视力提高42眼（13.0%）,视力不变215眼（66.4%）,视力下降67眼（20.7%）;有效控制视网膜病变261眼,有效率高达80.6%;激光光凝术治疗有效率比较：1型糖尿病患者（53.8%）显著低于2型糖尿病患者（81.7%）,高危增殖期DR患者（41.4%）显著低于非增殖期（90.3%）及早期DR患者（87.5%）,糖化血红蛋白≥8.0%的DR患者（64.7%）显著低于糖化血红蛋白〈8.0%的DR患者（90.8%）,以上两两比较差异均具有统计学意义（P〈0.05）。结论激光光凝术可有效阻止DR病情进一步恶化,保护患者视力;影响其疗效的主要因素包括糖尿病分型、DR分期及血糖控制水平;把握光凝术时机、早期发现、早期治疗、积极控制血糖是治疗DR的关键。
Objective To discuss the efficacy and factors affecting the laser photocoagulation in treating diabetic retinopathy（DR）.Methods 324 eyes of 186 DR patients were selected as the objectives received laser photocoagulation.Follow-up lasted for 4 to 24 months after surgery（16.2months on average）.Results Of the 324 eyes,42 were improved（13.0%）,215 remained unchanged（66.4%） and 67 worsened（20.7%）.261 eyes were effectively controlled in DR,accounting for 80.6%.Efficiency of type I diabetic patients（53.8%） was significantly lower than that of Type II diabetic patients（81.7%）,with P0.05;that of high-risk proliferation DR patients（41.4%） was significantly lower than that of non-proliferation（90.3%） and early-phase DR patients（87.5%）,with P0.05;that of DR patients with glycosylated hemoglobin ≥8.0%（64.7%） was significantly lower than that of DR patients with glycosylated hemoglobin 8.0%（90.8%）,with P0.05.Conclusion Laser photocoagulation may effectively control the depravation of DR and protect the sight of patients.Factors affecting its curative effect include types of diabetes,DR phases and control level of diabetes.Time of using laser photocoagulation,early diagnosis,early treatment and active control of blood sugar are the keys to treating DR.
出处
《海南医学》
CAS
2011年第12期42-44,共3页
Hainan Medical Journal
