摘要
目的采用蒙特利尔认知评估量表(MoCA)分析帕金森病(PD)患者的认知功能损害的特点,并探讨MoCA在评估PD认知功能方面的应用价值。方法采用MoCA对35例PD患者进行认知功能评估,并进行各认知域的分析。结果 (1)本组研究对象的MoCA评分为20.51±5.767,其中7例患者MoCA≤26分,占20.0%;(2)PD患者各认知域障碍的发生率不一致,依次为语言(34例,97.1%)、延迟记忆(32例,91.4%)、视空间与执行能力(30例,85.7%)、抽象思维(27例,77.1%)、注意(23例,68.6%)、命名(13例,37.1%)和定向力(12例,34.3%);(3)MoCA的各认知域与总分的相关系数都大于0.50,P<0.01。结论 (1)MoCA是评估PD患者认知功能的高效快捷的工具;(2)PD患者常见的认知功能损害包括语言、延迟记忆、视空间与执行能力、抽象思维和注意,而命名和定向力相对损害较轻。
Objective To analyze the characteristics of cognitive function impairment in the patients with Parkinson＇s disease（PD） by Chinese version of Montreal cognitive assessment（MoCA） and to explore the application of MoCA in the patients with PD.Methods Thirty-five patients with PD were detected by MoCA and the results were analyzed.Results The total score of MoCA in patients with PD were 20.51±5.767,and there were seven patients less than 26.The incidences were different in the impairment of each cognitive domain of PD.It was indicated by the relevance analysis between each cognitive domain and total score in MoCA that attention,visual space and executive capacity were relevant closely with the total score in the scale.Conclusion MoCA could be used as a tool in clinical study of cognitive function for PD.Cognitive domain damage of PD were language,memory,visual space and executive capacity,Abstraction and attention.
出处
《中风与神经疾病杂志》
CAS
CSCD
北大核心
2011年第6期517-519,共3页
Journal of Apoplexy and Nervous Diseases
基金
国家自然科学基金(No.30870863
No.30801219)
广东省自然科学基金(10151008004000030)
广东省科技计划项目(2009B030801251)
广东省医学科研基金(No.A2009038)
关键词
帕金森病
认知功能损害
蒙特利尔认知评估量表
Parkinson disease
Cognitive function impairment
Montreal cognitive assessment
