摘要
目的分析粤西地区近20年来2507例胃癌临床流行病学特征的变化情况，探讨其变化规律及可能的发展趋势。方法总结分析粤西地区广东医学院附属医院等五家医院自1990～2009年经病理确诊为胃癌的2507例资料，将20年资料按每5年为-时期进行分析。结果2005—2009年段与1990～1994年段相比较，胃癌的收治率增加了147％，平均每年上升7．35％；发病中位年龄从53岁上升至59岁，上升了6岁；男女比例从2．91下降至2．24；发病部位胃窦从42．66％下降至40．13％，胃底贲门从22．39％上升至23．29％，胃角从8．88％上升至10．39％，胃体增加缓慢，而幽门管无明显变化；组织分化高中分化从76．06％下降至64．34％，低未分化从23．94％上升至35．66％；平均住院时间从18．25天降至15．46天，首发至初次确诊的平均时间从41．85个月降至15．78个月；城镇比例从24．44％上升至45．35％，乡村比例从75．56％下降至54．65％。结论近20年来粤西地区胃癌的发病趋势复杂化。
Objective To analyze and predict the trends in the clinical characteristics of 2507 cases of gastric cancer during the past twenty years in the western region of Guangdong province. Methods The clinical data of 2507 cases of gastric cancers confirmed patho- logically were analyzed. These patients were hospitalized to affiliated hospital of guangdong medical college and other four hospitals in the western region of Guangdong province, 1990 - 2009 and were divided into four 5 - year groups. Results The hospitalization number of gastric cancer in the 2005 ~ 2009 5 - year period was 147% ,which was higher than that of the 1990 - 1994 period with an annual increase of 7.35 %. The median age of patients in 2005 - 2009 was 59 years, with 6 years higher than that in 1990 - 1994. The male to female rati- o in 2005 - 2009 was 2.24： 1, which was lower than that in 1990 - 1994 （2.91：1 ）. The proportion of gastric antrum cancer in 2005 - 2009 was 40.13% ,which was lower than that in 1990 - 1994（42.66% ）. While the proportion of gastrocardiac carcinoma in 2005 - 2009 was 23.29% , which was higher than that in 1990 - 1994 （22. 39% ）. And the cancer in stomach corner increased from 8. 88% to 10.39%. The increase of stomach body was slight, and there was no obvious change in the pylorus. The moderately and well differentia- ted cancer dropped from 76.06% to 64.34% , and the poorly differentiated cancer rose from 23.94% to 35.66%. The average length of time decreased from 18.25 clays to 15.46 days, and the average time of first symptoms to the first diagnosed fell from 41.85 months to 15.78 months. The proportion of patients in town 2005 - 2009 was 45.35% , which was higher than that in 1990 - 1994（24.44% ） , while the pro- portion of patients in rural 2005 - 2009 was 54.65% , which was lower than that in 1990 - 1994（75.56% ）. Conclusion The trends in the clinical characteristics of gastric cancer during the past twenty years are more complex in the western region of Guangdong province.
出处
《医学研究杂志》
2011年第6期63-66,共4页
Journal of Medical Research
基金
2009年度广东医学院大学生科研立项基金资助项目(09SZY007)
关键词
胃癌
流行病学
临床特征
趋势
Gastric cancer
Epidemiology
Clinical characteristics
Trends
