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一种新的砷暴露标志物-唾液砷 被引量：4

Salivary Arsenic,A New Biomarker of Arsenic Exposure
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摘要 慢性砷中毒是一种严重危害人类健康的公共卫生疾病,其中毒机制尚不明确且无有效的治疗手段,因此早期的砷暴露筛查尤为重要。找到一种快速、简便的砷暴露检测标志物是预防砷中毒的关键。由于唾液有采样方便,无创伤,易储存,对不同年龄段的人群均适合等一系列优点,近年来唾液标本已广泛的应用到各种疾病及有害因子的诊断和检测当中,包括砷暴露的检测。该文就近年来唾液检测的应用及唾液砷作为砷暴露标志物的可行性等方面研究做一综述。 Arsenism is a serious public health hazard to human health.The mechanism for understanding arsenic toxicity remains vague and there is still no effective treatment for arsenism so far.Finding a quick and simple biomarker of arsenic exposure is crucial to the prevention of arsenism.Because saliva is easy to collect and store,noninvasive,suitable for all age groups,saliva has been widely used in recent years to diagnose various diseases and detect environmental pollutants,including arsenic exposure.This article reviewed the application of saliva testing and the feasibility of salivary arsenic as a biomarker of arsenic exposure.
作者 王大朋 刘建 安艳
机构地区 苏州大医学部放射医学与公共卫生学院
出处 《环境与健康杂志》 CAS CSCD 北大核心 2011年第6期561-563,共3页 Journal of Environment and Health
基金 日本文部科学省日本学术振兴会研究辅助金项目(20390173) 江苏省放射医学与防护重点实验室开放课题(KJS0927) 苏州大学国家自然科学基金预研项目(Q3126982)
关键词 唾液 砷暴露 生物标志物 Saliva Arsenic exposure Biomarker
分类号 R181.3 [医药卫生—流行病学]
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参考文献31

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二级参考文献13

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环境与健康杂志
2011年 第6期

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