摘要
目的探讨甲状腺彩色多普勒超声图像中的钙化灶对甲状腺结节良恶性鉴别的临床意义。方法对347例行甲状腺手术患者的病理检查结果与其术前甲状腺彩色多普勒超声图像进行回顾性比较研究。结果病理检查结果显示,甲状腺恶性结节102个(恶性组),良性结节384个(良性组)。恶性组钙化灶及微钙化灶构成比分别为69.6%(71/102)、45.1%(46/102),均显著高于良性组的18.5%(71/384)、1.0%(4/384,P值均<0.01)。去除性别因素后,≤45岁亚组中恶性甲状腺结节的钙化灶构成比为81.6%(31/38),微钙化灶构成比为68.4%(26/38),均显著高于>45岁亚组[62.5%(40/64)、31.2%(20/64),P值均>0.01]。结论彩色多普勒超声图像中的钙化灶是甲状腺癌的一项特异性指标,一旦超声检查发现甲状腺内有钙化灶,尤其是微钙化灶,年龄<45岁且伴较大结节者,应该高度警惕癌变风险。
Objective To investigate the clinical value of thyroid sonographic calcification in differentiating benign and malignant thyroid nodules. Methods The sonographic （color Doppler ultrasound） and pathological data of 347 patients who underwent thyroidectomy were studied retrospectively. Results The rates of calcification （69.6%） and microcalcification rate （45.1% ） in the malignant group were significantly higher than those in the benign group （ 18.5% vs, 1.0%, P〈0.01） ; after adjusting the sex factor, patients who aged≤45- year-old had a significantly higher calcification （81. 6% vs. 62. 5%） and microcalcifiction rate （68. 4% vs. 31.2%） compared with those aged 〉 45-year-old. Conclusion Sonographic thyroid calcification is a specific marker for thyroid cancer. Especially when there are microcalcifications in patients younger than 45 years old and with larger nodules, possibility of malignant transformation should be considered. （Shanghai Med J, 201], 34： 364-366）
出处
《上海医学》
CAS
CSCD
北大核心
2011年第5期364-366,共3页
Shanghai Medical Journal
关键词
超声检查
甲状腺结节
钙化
微钙化
UItrasound
Thyroid nodules
Calcification
Microcalcifications
