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骨肉瘤动物模型的研究概况

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摘要 骨肉瘤也称成骨肉瘤,是骨的原发性恶性肿瘤,在骨原发性肿瘤中发生率仅次于浆细胞骨髓瘤。多见于青少年,男性多于女性,约为2:1,好发于长骨干骺端,发病率高,预后较差,是青少年与恶性肿瘤相关第二大死亡因素。关于骨肉瘤的病因、发病机制及转移的相关机制不甚明了。构建人类骨肉瘤动物模型,对骨肉瘤的进一步研究和新的抗骨肉瘤药物初步筛选和疗效评价,具有很重要的意义。
作者 杨德建 张俐
出处 《按摩与康复医学》 2011年第13期38-42,共5页 Chinese Manipulation and Rehabilitation Medicine
基金 教育部新世纪优秀人才支持计划(编号:NECT-09-0013) 2.福建省高校新世纪优秀人才支持计划(编号:闽教科200635号) 3.卫生部科学研究基金(编号:WKJ2008-2-042)
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