摘要
目的:探讨结节性胃炎的临床特点及与幽门螺杆菌(Hp)的关系,以提高对其的认识。方法:观察诊断为结节性胃炎患者的内镜、病理表现,以及Hp感染情况和根除治疗的效果。结果:33例结节性胃炎病例中,内镜下表现特点为:以胃窦部为主,大小均匀的结节样或颗粒样改变。Hp感染率93.9%,病理检查提示胃黏膜呈中度至重度炎症改变,淋巴滤泡发生率69.6%。明显高于其他胃炎。经给予质子泵抑制剂为基础的三联疗法根除治疗后,随着Hp的根除。临床症状消失,淋巴滤泡消失,病理炎症程度减轻。结论:结节性胃炎为Hp感染的一种特殊征象,是慢性胃炎的一种特殊内镜下表现,是Hp感染的内镜指标,提示对结节性胃炎应考虑Hp根除治疗。
Objective To investigate the clinical characteristics of nodular gastritis and the relationship between it and helicobacter pylori （Hp）. In this way, we can improve the cognition of it. Methods ： Endoscopic, pathologic manifestation,infection situation of Hp and eradication effect of 33 nodular gastritis diagnosed by our hospital were analyzed. Results The endoscopic manifestations were size uniform nodular or Particle Like changes mainly located in gastric antrum, rate of Hp infection was 93.9%. There existed moderate or severe inflammation and the incidence of lymphoid follicles in gastric mucosa was 69. 6% which was evidently higher than other gastritis. After the patients were cured with triple regimens based on proton pump inhibitor, clinical manifestations disappeared with the eradication of Hp,the degree of pathological inflammation reduced and lymphoid follicles disappeared. Conclusion： Nodular gastritis in adult is a special sign of Hp infection, nodular pathological change is a special endoscopic manifestation of chronic gastritis and is all endoscopic marker of Hp infection. It may suggest that nodular gastritis in children must consider eradication therapy of Hp.
关键词
结节性胃炎
幽门螺杆菌
根除治疗
Nodular gastritis
Helicobacterpylori （Hp）
Eradication therapy
