摘要
目的观察白内障超声乳化术后十眼变化。方法前瞻性非随机研究，符合条件的术前非十眼的白内障手术48例（48眼），均行11点位角膜缘隧道切口的超声乳化吸出联合人工晶状体植入术。记录手术持续时间、超声能量时间，手术前及手术后（7d、1个月、3个月）进行干眼的症状评分，检测泪膜破裂时间（tBUT）、SchirmerI试验（ST-I）。结果失访4例，退出2例，完成随访者42例42眼；术后7d症状评分较术前显著增加（P〈0．01），术后1个月、3个月症状评分与术前差异无统计学意义（P〉0．05）；术后7d、1个月、3个月tBUT与术前相比均显著降低（P〈0．01）。术后7d、1个月ST-I与术前差异无统计学意义（P〉0．05）；术后7d、1个月ST-I较术前显著减少（P〈0．05），术后3个月、3个月的症状评分、tBUT、ST-I与手术时间显著相关（P〈0．05），与超声能量时间无显著相关（P〉0．05）。结论白内障行超声乳化术后可出现千眼；术后初期，干眼症状、泪膜稳定性和泪液分泌量均减少，随时间延长，干眼症状和泪液分泌量逐渐向术前水平恢复，但术后3个月泪膜稳定性仍较荨；干眼表现可能与手术时间有关。
Objective To observe changes of dry eye after cataract phacoemalsification surgery. Methods Prospective non-randomized study. Forty-eight eyes from 48 patients without preoperative dry eye werc involved. Dry eye symptoms score, tear break-up time （ t BUT） and Schirmer I test （ST- I ） were measured before surgery and 7 days, 1 month,3 months after surgery. Operation time under microscope and phacoemusification time were record. Statistical analyses were performed. Results Four cases were lost to follow up, two cases withdrew, and forty-two cases completed follow up. Symtoms score at 7 days postoperatively increased significantly compared with the preoperative values （ P 〈 O. O1 ）, shile symptoms score at l month,3 months postoperatively was not significant different from preoperative values （P 〉 O. 05 ）. Tear break-up time at any postoperative timepoint were worse than preoperative values （ P 〈 0. O1 ）. ST- I at 7 days and 1 month postoperatively were worse than preoperative values （P 〈 0.05） , and ST- I at 3 months postoperatively were not different from preoperative values （ P 〉 0.05 ）. Significant correlation was noted between symptoms score, tBUT, ST- I at any postoperative timepoint and operation time under microscope. There was no correlation between symptoms score, tBUT, ST- I at any postoperative timepoint and phacoemusification time. Conclusion Dry eye may occur after cataract surgery. Dry eye symptoms,tear film stability and tear secretory valume are worse in early postoperative period,and dry eye symptoms and tear secretory valume are gradually restored with time, while tear film stability is still less at 3 months postoperativly. Operation time under microscope may have an adverse effect on dry eye.
出处
《中华眼外伤职业眼病杂志》
2011年第6期452-455,共4页
Chinese Journal of Ocular Trauma and Occupational Eye Disease
关键词
白内障超声乳化手术
干眼
泪液
eataraet phacoemalsification surgery
dry eye
tear
