摘要
目的探讨内科保守治疗基础上联合低分子肝素对急性胰腺炎的治疗效果。方法确诊急性胰腺炎76例患者分为抗凝治疗组(39例)及对照组(37例),均给予内科保守治疗,抗凝治疗组在此基础上给予低分子肝素4100 IU皮下注射,1次/12小时,疗程2周,比较两组治疗效果。结果抗凝治疗组总有效率92.30%,对照组总有效率75.68%,差异有统计学意义(χ2=15.93,P<0.001)。抗凝治疗组应用低分子肝素治疗前后凝血酶原时间、部分活化凝血酶原时间、国际标准比率、纤维蛋白原比值比较,差异均无统计学意义(P>0.05)。治疗期间患者均未出现消化道出血、颅内出血等出血倾向。结论内科保守治疗基础上联合低分子肝素治疗急性胰腺炎是安全、有效的,初步观察能明显降低死亡率。
Objective To study the influence of lower molecular weight heparin in the treatment of patients with acute pancreatitis.Methods Seventy-six patients with acute pancreatitis were divided into anticoagulation group(n=39)and control group(n=37).The prognosis of patients was detected.Results Treatment with lower molecular weight heparin significantly decreased the white blood cell count and the levels of serum and urine amylase,improved the cureless rate,decreased worse rate and mortality of patients with acute pancreatitis.Secondary not improve the bleeding rate.Conclusion Treatment with lower molecular weight heparin is safe,effective and decreases the mortality rate.
出处
《实用医院临床杂志》
2011年第4期103-104,共2页
Practical Journal of Clinical Medicine
关键词
低分子肝素
急性胰腺炎
疗效
Lower molecular weight heparin
Acute pancreatitis
Effect
