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抗凋亡因子cFLIP在延边黄牛性周期黄体中表达的研究 被引量：4

Research on Expression of Anti-apoptosis Factor cFLIP in Estrous Cycle Corpus Luteum of Yanbian Yellow Cattle
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摘要 为了研究延边黄牛黄体中抗凋亡因子(Cellular FLICE-like inhibitory protein:cFLIP)的变化情况及其与细胞凋亡的关系,本实验采用免疫染色方法,观察cFLIP在延边黄牛周期黄体中的表达变化,并从组织化学角度分析了cFLIP作为抗凋亡因子参与延边黄牛的黄体退化。 To study the expression of cellular FLICE inhibitory protein（cFLIP）,anti-apoptotic protein,and the relationship with cellular apoptosis in the corpus luteum（CL） of Yanbian yellow cattle,the immunostaining method was used to observe cFLIP expression changes in corpus luteum（CL） during estrous cycle in Yanbian yellow cattle.The process that cFLIP participated in Yanbian yellow cattle corpus luteum regression as an anti-apoptosis factor was also analyzed based on histochemistry view.
作者 尹多 方南洙 李钟淑 蔡丽娟 金花子
机构地区 延边大学农学院动物科学系
出处 《西南农业学报》 CSCD 北大核心 2011年第3期1119-1121,共3页 Southwest China Journal of Agricultural Sciences
基金 国家自然科学基金(30860184) 延边大学211工程三期立项项目
关键词 延边黄牛 黄体 细胞凋亡 染色 Yanbian yellow cattle Corpus luteum Apoptosis Stain
分类号 S823.81 [农业科学—畜牧学]
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参考文献5

  • 1Matsuda-Minehata F, Goto Y, Inoue N, ct al. Changes in expression of anti-apoptotic protein, cFLIP, in granulosa cells during follicular atrcsia in porcine ovaries[J]. Molecular Reproduction and Develop- ment, 2005, 72(2):145-51.
  • 2Matsuda F, Inoue N, Goto Y, et al. cFLIP regulates death receptor- mediated apoptosis in an ovarian gnmulma cell line by inhibiting pro- caspase-8 cleavage [ J ]. J Reprod Dev, 2008,54 ( 5 ) : 314 - 20.
  • 3Sakumoto R, Komatsu T, Kasuya E, et al. Expression of mRNAs for interleukin-4, interleukin-6 and their receptors in porcine corpus lu- teum during the estrous cycle [J]. Endocrinology, 2006, 31 : 246 - 257.
  • 4Manabe N, Goto Y, Matsuda-Minchata F, et 81. Regulation mecha- nism of selective atresia in porcine follicles: regulation of granulesa cell apoptosis during atreia [ J ]. J Reprod Dev. , 2004, 50 : 493 - 514.
  • 5Hojo T, OmarAL-ZIAABI M, Kom/yama J, eta]. Expression and Lo- calization of cFLIP, an Anti-apoptotic Factor, in the Bovine Corpus Luteum [J]. Journal of Reproduction and Development, 2010, 56 (2) :230 -235.

同被引文献66

  • 1杨晓菁,姚红军,王玉凤.哺乳动物卵母细胞凋亡的研究进展[J].动物学杂志,2004,39(6):101-106. 被引量：18
  • 2卜兴江.细胞凋亡研究进展[J].生物学教学,2006,31(12):7-9. 被引量：3
  • 3杨绍杰,孟金萍,屈祎,刘云波.细胞凋亡信号传导通路的研究进展[J].中国比较医学杂志,2007,17(5):297-301. 被引量：72
  • 4王颖,张庆涛,岳文斌.细胞凋亡与哺乳动物配子发生[J].上海畜牧兽医通讯,2007(1):51-53. 被引量：3
  • 5Manabe N, Goto Y, Matsuda-Minehata F, et al. Regula- tion mechanism of selective atresia in porcine follicles: Regulation of granulosa cell apoptosis during atresia [J]. J Reprod Dev, 2004,50 : 493-514.
  • 6Nagata S. Apoptosis by death factor [-J]. Cell, 1997, 88:355-365.
  • 7Irmler M, Thome M, Hahne M, et al. Inhibition of death receptor signals by cellular FLIP[J]. Nature,1997,388:190-195.
  • 8Sakumoto R, Komatsu T, Okuda K, et al. Expression of mRNAs for interleukin-4, interleukin-6 and th,ir re- ceptors in porcine corpus luteum during the estrous cyele[J]. Endocrinology, 2006,31 : 246-257.
  • 9Thompson C B. Apoptosis in the pathogenesis and treatment of disease[J]. Science, 1995,267 : 1456.
  • 10Selvaraju S,Raghavendrs B S, Subramani T S, et al. Changes in luteal cells distribution, apoptotie rate, lipid peroxidation levels and antioxidant enzyme ac- tivities in buffalo (Bubalus buhalis) corpus luteum [J]. Anim Reprod Sci, 2010,120(i/4) : 39-46.

引证文献4

二级引证文献15

西南农业学报
2011年 第3期

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