摘要
目的探讨干扰素治疗原发性肝癌的疗效。方法对2006年9月～2010年8月在本科行根治性切除术后72例原发性肝癌患者的治疗效果进行回顾性分析。结果本研究中,行根治性手术切除术后再应用干扰素的患者中,2年内总的复发/转移率53.57%(15/28),2年生存率50.00%(14/28);接受单纯根治性手术切除治疗的患者2年内总的复发/转移率68.18%(30/44),2年生存率29.55%(13/44)。根治性切除联合干扰素治疗原发性肝癌的治疗效果明显优于单纯行根治性手术切除。结论干扰素可减少肝癌患者根治性切除术后的复发与转移,提高生存率。
Objective To evaluate the therapeutic effect of interferon-α（IFN-α） in patients with primary liver cancer.Drugs were given after tumor removment.Methods Seventy-two cases of primary liver cancer were retrospectively analyzed in our department from September 2006 to August 2010.All 72 cases were treated with radical resection.And among them 28 cases were treated with IFN-α2b,following radical resection.The others were treated by radical resection only.Retrospective analysis was done about the data.Results The ratio of recurrence/metastasis about combined treatment group was 53.57%,survival rate was 50% in two years,but that of the other group was 68.18% and 29.55%.The curative effect of IFN-α associated with radical resection was better than resection only.There was significant difference between the two groups（P0.05）.Conclusion Combined with IFN-α therapy after radical resection in patients with primary liver cancer can be useful to decrease ratio of recurrence and metastasis after tumor removment andenhance the survival rate.
出处
《实用临床医药杂志》
CAS
2011年第11期133-134,139,共3页
Journal of Clinical Medicine in Practice
关键词
干扰素
原发性肝癌
联合治疗
IFN-α
primary liver cancer
combined therapy
