摘要
目的：探讨肿瘤血管生成与胃癌生物学特性之间的关系。方法：采用免疫组织化学Ｓ－Ｐ法，检测４１例胃癌手术标本ＦⅧ因子相关抗原，进行微血管（ＭＶ）计数，并结合临床病理特征进行分析。结果：Ⅰ、Ⅱ期、高分化及无淋巴转移胃癌的ＭＶ计数分别低于Ⅲ～Ⅳ期（Ｐ＜０．０５）低中分化（Ｐ＜０．００２，Ｐ＜０．０１）及有淋巴转移胃癌（Ｐ＜０．０１）。
Objective: To study the relationships between angiogenesis and biologic features of gastric carcinoma. Methods: The F -RA(Factor-Related antigen)was detected in 41 resected species,and its clinical pathologic significanc was analyed. Results: The MV counts of the well differentiated and non-lymphatic metastasis groups in the stages, were lower than those of the porly and moderately differentiated ( P<0.002,P <0.01)and lymphatic metsatasis groups( P <0.001) in the stage ( P <0.05). Conclusion The MV count may be the judgment of the malignant biologic behavior and propensity for lymphatic metastasis in gastric cancer.
出处
《郧阳医学院学报》
1999年第2期66-67,共2页
Journal of Yunyang Medical College
关键词
胃肿瘤
新生血管化
淋巴转移
生物学特性
Stomach Neoplasm
Immunohistochemistry
Neovascularization
Lymphatic Metastasis
