摘要
采用不同溶剂进行溶解情况筛选小儿氨酚烷胺滴鼻剂的处方工艺,合理处方进行药效学研究。处方的较佳辅料为:1,2-丙二醇∶水=1∶1的混合溶剂,该滴鼻剂具有较好的解热、镇痛和抗炎作用,无刺激性,配制工艺简单,使用方便,疗效确切,值得进一步研究。
To screen the process of nasal drops of pediatric paracetamol and amantadine hydrochloride and to screen dissolution in different solvents,the reasonable prescription pharmacodynamics were studied.Better materials for the prescription was 1,2-propanediol:water=1:1 mixed solvent,and the nasal drops had a good antipyretic,analgesic and anti-inflammatory effects,and non-irritating.Pediatric paracetamol and amantadine hydrochloride nasal drops preparation process was simple,easy to use and effective,and worthy of further study.
出处
《广州化工》
CAS
2011年第13期85-86,共2页
GuangZhou Chemical Industry
基金
大理学院青年基金
编号(2006x28)
云南省教育厅基金
编号(07Z40368)
关键词
滴鼻剂
处方
药效学
nasal drops
prescription
pharmacodynamics