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荨麻疹外周血T淋巴细胞及亚群的检测 被引量:43

Determination of peripheral blood T lymphocytes and their subsets in patients with urticaria
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摘要 对60例荨麻疹患者用流式细胞仪检测外周血T淋巴细胞及其亚群并与20例健康志愿者作对照。结果表明 ,荨麻疹患者CD3+及CD4 +细胞明显降低 ,与健康对照组比较差异有非常显著性意义(P<0.01),其中以急性荨麻疹患者CD3+、CD4+改变最为明显。实验结果表明 ,荨麻疹患者存在着T淋巴细胞免疫功能紊乱现象 ,在荨麻疹的发病中 ,不但有体液免疫参与 ,而且细胞免疫在荨麻疹的发病中亦有一定的作用。 The peripheral blood T lymphocytes and their subsets in 60 patients with urticaria were detected by flow cytometry and compared with 20 healthy controls. The results showed that the number of CD3+and CD4+cells in the urticaria group was significantly lower than that of control group (P< 0.01), especially in patients with acute urticaria. The results showed that there was immunologic dysfunction of T lymphocyte in the patients with urticaria. It is the author's opinion that not only humoral immunity takes part but also cellular immunity plays a definite role in the pathogenesis of urticaria.
作者 唐亚娟
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 1999年第5期284-285,共2页 Journal of Clinical Dermatology
关键词 荨麻疹 T细胞亚群 流式细胞仪 T细胞 Urticaria T lymphocyte subset Flow cytometry
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参考文献1

  • 1马桢林(译),国外医学皮肤性病学分册,1998年,24卷,4期,235页

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